New & Used 2026 Mercedes-Benz E-Class for Sale near San Ysidro, CA

Compare 2026 Mercedes-Benz E-Class Trims

The E-Class offers a blend of luxury and performance, with options ranging from budget-friendly to high-performance hybrids.

• Starting at $62,634
• Best MPG/MPGe: 52 city / 64 hwy
• Most Popular: E 350 4MATIC

Trim Overview

Prices updated weekly from CarGurus listings.

Quick Compare Table

Listing prices sourced from CarGurus — updated weekly. OEM specs from manufacturer data.

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Trim Deep Dives

E 350 RWD — "Who It's For"

The E 350 RWD is the pick for shoppers who want a luxury sedan without the AWD price premium. It's the most budget-friendly option in the lineup.

• Avg. market price: $62,634 (updated weekly)
• MPG/MPGe: 25 city / 33 hwy
• Inventory: 538 listings
• View E 350 RWD listings

E 350 4MATIC — "Who It's For"

The E 350 4MATIC is the pick for shoppers who want all-wheel drive without stepping up to a higher price point. It's also the most popular trim in the lineup.

• Avg. market price: $69,692 (updated weekly)
• MPG/MPGe: 24 city / 33 hwy
• Inventory: 882 listings
• View E 350 4MATIC listings

E 450 4MATIC — "Who It's For"

The E 450 4MATIC is the pick for shoppers who want sporty performance and luxury features without going for the top-tier model.

• Avg. market price: $79,972 (updated weekly)
• MPG/MPGe: 22 city / 31 hwy
• Inventory: 169 listings — lower availability; may limit negotiating room
• View E 450 4MATIC listings

AMG E 53 Hybrid 4MATIC+ — "Who It's For"

The AMG E 53 Hybrid 4MATIC+ is the pick for shoppers who want a high-performance luxury sedan with hybrid efficiency.

• Avg. market price: $97,256 (updated weekly)
• MPG/MPGe: 52 city / 64 hwy
• Inventory: 101 listings — lower availability; may limit negotiating room
• View AMG E 53 Hybrid 4MATIC+ listings

Trim Recommendations

Most Popular — E 350 4MATIC

With 882 active listings, the E 350 4MATIC is the clear volume leader in the lineup.

Browse E 350 4MATIC listings

Best Budget Option — E 350 RWD

At $62,634 avg market price — below the lineup median of $74,832 — it's the most accessible entry point.

Browse E 350 RWD listings

Best for Fuel Economy — AMG E 53 Hybrid 4MATIC+

With an impressive MPG/MPGe of 52 city / 64 hwy, this hybrid is the most fuel-efficient option.

Browse AMG E 53 Hybrid 4MATIC+ listings

These recommendations are based on CarGurus' proprietary market data from September 2, 2026, CarGurus experts' opinions, and generative AI.

Is the 2026 Mercedes-Benz E-Class a good car?

The 2026 Mercedes-Benz E-Class earns 7.33/10 from our experts. The model scores 8/10 across Look and feel, Performance, Technology, and Safety.

It stands out for keeping the wagon body style alive while also offering a sedan, and it adds a standard biometric fingerprint scanner to authenticate saved driver profiles. That makes it especially appealing if you want something more versatile than an SUV without giving up technology or driving character.

The trade-offs are real, though: the brakes can be squealing and grabby, and the back seat is cramped. Advanced safety features are not standard.

With 32.9% of listings priced as good or great deals, there’s some room to shop carefully.

Is the 2026 Mercedes-Benz E-Class reliable?

The 2026 Mercedes-Benz E-Class is presented as a modern, tech-forward luxury car, and its plug-in hybrid wagon setup is described as efficient for short trips while still using gasoline for longer drives. The performance write-up also points to a powertrain that feels strong and well-integrated in everyday use.

It includes a plug-in hybrid system with a turbocharged inline-six, electric motor, and battery, and the expert evaluation notes that the car can be recharged regularly and still deliver strong real-world efficiency. The cost-effectiveness discussion also frames it as a strong value relative to rival performance wagons because of its efficiency and capability.

If you’re buying used, the main long-term ownership risk is that this is a complex luxury performance hybrid, so you should expect maintenance and repair exposure to be higher than with a simpler mainstream car.

What should I look for when buying a used 2026 Mercedes-Benz E-Class?

Accident-free inventory is excellent at 97.1% — clean inventory, standard diligence applies.

You should still run a history report and prioritize a pre-purchase inspection, especially on a car with performance hardware and advanced electronics. Focus on how the brakes feel in traffic, whether the cabin shows heavy wear on touch surfaces, and whether the tech features operate cleanly and consistently.

Key things to evaluate:

• Trim level: The E 450 All-Terrain is the less-expensive wagon, while the AMG E 53 Hybrid is the performance upgrade. The All-Terrain has a more rugged look and technology that can assist with light off-road travel, while the AMG model is tuned for paved-road performance. Base equipment includes MB-Tex artificial leather, natural grain wood trim, a 12.3-inch digital instrumentation panel, and a 14.4-inch infotainment touchscreen, but the test vehicle’s upgraded packages added items such as the Superscreen and premium leather.
• Powertrain: The AMG E 53 Hybrid wagon uses a turbocharged 3.0-liter inline-six paired with a 120-kilowatt electric motor and a 21.2-kilowatt-hour battery. Total output is 577 hp and 553 lb-ft, with 604 hp available with Race Start active. It is rated at 41 miles of electric range and 22 mpg combined in hybrid mode.
• Safety package: The standard safety setup includes high-beam assist, forward-collision warning, automatic emergency braking, blind-spot monitors, an exit warning system, a surround-view camera system, front and rear parking sensors, semi-autonomous self-parking, Pre-Safe forward-collision preparation, Pre-Safe Sound, and SOS emergency call service. The Driver Assistance Package adds adaptive cruise control, active blind-spot monitoring, active intersection assist, active emergency stop assist, active lane-change assist, active lane-keep assist, active steering assist, automatic lane change capability, evasive steering assist, congestion emergency braking, and Pre-Safe collision preparation for rear and side impacts.
• Infotainment: The standard setup includes a 12.3-inch digital driver display and a 14.4-inch infotainment touchscreen. Wireless Apple CarPlay and Android Auto are standard, along with augmented reality navigation, music streaming, and Burmester 4D surround sound with Dolby Atmos. The Superscreen package adds a 12.3-inch passenger touchscreen and an interior selfie and video camera.
• Fuel efficiency: The AMG E 53 Hybrid wagon is rated at 41 miles of electric range and 22 mpg combined in hybrid mode. In testing, it averaged 47.4 mpg over the first 250 miles when regularly recharged, with 52% of miles driven on electricity.

Which 2026 Mercedes-Benz E-Class trim should I buy?

The 2026 Mercedes-Benz E-Class is offered in 4 trim levels: E 350 Sedan, E 450 Sedan, E 450 All-Terrain Wagon, AMG E 53 Hybrid Sedan.

Here's the short version:

• E 350 Sedan: This is the entry point if you want the E-Class experience with the least expensive starting position. It suits you if you care more about getting into the lineup than chasing the most power or the most specialized hardware.
• E 450 Sedan: This is the better all-around sedan choice if you want more performance and a richer feel without moving all the way to the AMG model. It should appeal if you want a balanced luxury sedan rather than the most extreme version.
• E 450 All-Terrain Wagon: This is the wagon for you if you want the more rugged look and the light off-road travel assistance mentioned in the review. It’s the practical pick if you want wagon utility without stepping into AMG pricing.
• AMG E 53 Hybrid Sedan: This is the performance-focused choice, and it’s the one to buy if you want the strongest driving character in the lineup. It pairs the hybrid powertrain with AMG hardware and is the clear enthusiast pick.

The safety package note is simple: advanced safety features are not standard, so you should look closely at whether a given car has the Driver Assistance Package.

Is now a good time to buy a used 2026 Mercedes-Benz E-Class?

This looks like a moderate, selective buyer’s market, so you can shop with some leverage but should still move quickly on the right car.

• Deal availability: 32.9% of listings are priced as good or great deals.
• Inventory: There are 657 listings available.
• Clean inventory: 97.1% of listings are accident-free.

If you find a listing below $67,394.64, that's toward the low end of the year-round range and worth acting on quickly.

Is the 2026 Mercedes-Benz E-Class safe?

The E-Class wagon does not have published NHTSA or IIHS ratings at the time of writing.

It earns a 8/10 safety score from our experts.

The standard safety equipment includes high-beam assist, forward-collision warning, automatic emergency braking, blind-spot monitors, an exit warning system, a surround-view camera system, front and rear parking sensors, a semi-autonomous self-parking system, Pre-Safe forward-collision preparation, Pre-Safe Sound, and SOS emergency call service.

The Driver Assistance Package adds adaptive cruise control, active blind-spot monitoring, active intersection assist, active emergency stop assist, active lane-change assist, active lane-keep assist, active steering assist, automatic lane change capability, evasive steering assist, congestion emergency braking, and Pre-Safe collision preparation for rear and side impacts. Advanced safety features are not standard, so you should verify that a used example has this package if you want the fullest suite.

Should I buy a 2026 Mercedes-Benz E-Class or consider a different year?

If you're weighing the 2026 against nearby model years, here's how to think about it:

Choose the 2026 if:

• 32.9% of listings are priced as good or great deals.
• Accident-free inventory is excellent at 97.1% — clean inventory, standard diligence applies.
• The 2026 adds a standard biometric fingerprint scanner and debuts the AMG E 53 Hybrid wagon, giving you a more modern and more distinctive lineup.

The bottom line: If you want the newest E-Class with the wagon body style, the fingerprint scanner, and the AMG E 53 Hybrid wagon, the 2026 is the one to target. If you’re more price-sensitive, you can keep shopping and focus on the best-equipped example rather than insisting on the newest year.

These recommendations are based on CarGurus' proprietary market data from September 4, 2026, CarGurus experts' opinions, and generative AI.