New & Used 2026 Mercedes-Benz E-Class for Sale near Charleston, SC

Compare 2026 Mercedes-Benz E-Class Trims

The E-Class offers a blend of luxury and performance, with options ranging from budget-friendly to high-performance hybrids.

• Starting at $63,320
• Best MPG/MPGe: 52 city / 64 hwy
• Most Popular: E 350 4MATIC

Trim Overview

Prices updated weekly from CarGurus listings.

Quick Compare Table

Listing prices sourced from CarGurus — updated weekly. OEM specs from manufacturer data.

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Trim Deep Dives

E 350 RWD — "Who It's For"

The E 350 RWD is the pick for shoppers who want a luxury sedan without the added cost of AWD. It's the most budget-friendly option in the lineup.

• Avg. market price: $63,320 (updated weekly)
• MPG/MPGe: 25 city / 33 hwy
• Inventory: 529 listings
• View E 350 RWD listings

E 350 4MATIC — "Who It's For"

The E 350 4MATIC is the pick for shoppers who want all-wheel drive without stepping up to a higher price point. It's also the most popular trim in the lineup.

• Avg. market price: $69,401 (updated weekly)
• MPG/MPGe: 24 city / 33 hwy
• Inventory: 922 listings
• View E 350 4MATIC listings

E 450 4MATIC — "Who It's For"

The E 450 4MATIC is the pick for shoppers who want sporty performance and luxury features without going for the top-tier model.

• Avg. market price: $79,364 (updated weekly)
• MPG/MPGe: 22 city / 31 hwy
• Inventory: 166 listings — lower availability; may limit negotiating room
• View E 450 4MATIC listings

AMG E 53 Hybrid 4MATIC+ — "Who It's For"

The AMG E 53 Hybrid 4MATIC+ is the pick for shoppers who want a high-performance luxury sedan with impressive fuel efficiency.

• Avg. market price: $96,716 (updated weekly)
• MPG/MPGe: 52 city / 64 hwy
• Inventory: 99 listings — lower availability; may limit negotiating room
• View AMG E 53 Hybrid 4MATIC+ listings

Trim Recommendations

Most Popular — E 350 4MATIC

With 922 active listings, the E 350 4MATIC is the clear volume leader in the lineup.

Browse E 350 4MATIC listings

Best Budget Option — E 350 RWD

At $63,320 avg market price — below the lineup median of $74,382 — it's the most accessible entry point.

Browse E 350 RWD listings

Best for Fuel Economy — AMG E 53 Hybrid 4MATIC+

With an impressive MPG/MPGe of 52 city / 64 hwy, this hybrid offers the best fuel efficiency in the lineup.

Browse AMG E 53 Hybrid 4MATIC+ listings

These recommendations are based on CarGurus' proprietary market data from September 12, 2026, CarGurus experts' opinions, and generative AI.

Is the 2026 Mercedes-Benz E-Class a good car?

The 2026 Mercedes-Benz E-Class earns 7.33/10 from CarGurus experts. The model scores 8/10 across Look and feel, Performance, Technology, and Safety.

For you, the appeal depends on what you want from the E-Class nameplate. The wagon body style keeps utility in the mix, and the lineup adds a standard biometric fingerprint scanner for saved driver profiles, which gives the cabin a more personal, tech-forward feel. The AMG E 53 Hybrid wagon is the standout if you want something beyond the usual SUV formula, because it combines plug-in hybrid efficiency with AMG-engineered performance and real-world practicality.

The trade-offs are clear: the brakes can be squealing and grabby, the back seat is cramped, and advanced safety features are not standard. Even so, the E-Class wagon remains a compelling choice if you want luxury, utility, and something uncommon in a market crowded with SUVs.

35.1% of listings are priced as good or great deals, which suggests there is still some room to shop selectively.

Is the 2026 Mercedes-Benz E-Class reliable?

The 2026 Mercedes-Benz E-Class is presented as a polished, well-engineered luxury car, with the expert notes emphasizing refined operation, strong tech execution, and a powertrain that can handle both short electric-only trips and longer gasoline-powered drives. The performance notes also point to a sophisticated plug-in hybrid setup with a turbocharged inline-six, a 120-kilowatt electric motor, and a battery that supports meaningful electric driving.

The expert notes also describe the car’s systems as operating with impressive transparency and natural behavior, which is a good sign for day-to-day dependability. On the cost side, the plug-in hybrid setup adds efficiency and can reduce how often you rely on gasoline, and the model is positioned as a strong value relative to pricier performance-wagon rivals.

For used buyers, the main long-term ownership risk is that this is a complex, high-performance luxury wagon with advanced hardware, so you should expect maintenance and repair exposure to be higher than with a simpler mainstream car.

What should I look for when buying a used 2026 Mercedes-Benz E-Class?

Accident-free inventory is excellent at 97.3% — clean inventory, standard diligence applies.

You should still run a history report and prioritize a pre-purchase inspection, especially on a performance-oriented wagon with advanced electronics and a plug-in hybrid system. Focus on how the brakes feel in normal traffic, whether the cabin tech behaves consistently, and whether the car’s condition matches its equipment level and mileage. If you’re shopping the AMG version, pay extra attention to wear items that can be affected by harder driving.

Key things to evaluate:

• Trim level: The E 450 All-Terrain is the less-expensive wagon, while the AMG E 53 Hybrid is the performance upgrade with a lower, more road-focused character. The test car’s Pinnacle trim, 21-inch forged alloy wheels, premium leather, and option packages show how quickly equipment can stack up, but the base setup already includes MB-Tex artificial leather, natural grain wood trim, a 12.3-inch digital instrument panel, and a 14.4-inch infotainment touchscreen.
• Powertrain: The AMG E 53 Hybrid uses a turbocharged 3.0-liter inline-six paired with a 120-kilowatt electric motor and a 21.2-kilowatt-hour battery. It delivers 577 hp and 553 lb-ft of torque, with 604 hp available with Race Start active, plus an EPA-rated 41 miles of electric range and 22 mpg combined in hybrid mode.
• Safety package: The standard setup includes high-beam assist, forward-collision warning, automatic emergency braking, blind-spot monitors, an exit warning system, a surround-view camera system, front and rear parking sensors, semi-autonomous self-parking, Pre-Safe forward-collision preparation, Pre-Safe Sound, and SOS emergency call service. The Driver Assistance Package adds adaptive cruise control, active blind-spot monitoring, active intersection assist, active emergency stop assist, active lane-change assist, active lane-keep assist, active steering assist, automatic lane change capability, evasive steering assist, congestion emergency braking, and Pre-Safe collision preparation for rear and side impacts.
• Infotainment: The cabin uses MBUX with a 12.3-inch digital driver display and a 14.4-inch infotainment touchscreen. Wireless Apple CarPlay and Android Auto are standard, along with augmented reality navigation, music streaming, and Burmester 4D surround sound with Dolby Atmos. The optional Superscreen adds a 12.3-inch passenger display and an interior camera.
• Fuel efficiency: The AMG E 53 Hybrid wagon is rated at 41 miles of electric range and 22 mpg combined in hybrid mode. In testing, it averaged 47.4 mpg over the first 250 miles with frequent recharging and 22.9 mpg when using gasoline only.

Which 2026 Mercedes-Benz E-Class trim should I buy?

The 2026 Mercedes-Benz E-Class is offered in 5 trim levels: E 350 Sedan, E 450 Sedan, E 450 All-Terrain Wagon, AMG E 53 Hybrid Sedan, AMG E 53 Hybrid Wagon.

Here's the short version:

• E 350 Sedan: This is the entry point if you want the E-Class experience in sedan form without moving up to the more expensive performance or wagon variants.
• E 450 Sedan: This is the stronger sedan choice if you want more power and a more upscale step up from the E 350 without going all the way to AMG pricing.
• E 450 All-Terrain Wagon: This is the least-expensive wagon, and it’s the one to consider if you want the wagon body style with a more rugged look and light off-road travel capability.
• AMG E 53 Hybrid Sedan: This is the performance-focused sedan choice, pairing AMG hardware with plug-in hybrid efficiency for buyers who want speed and tech in a traditional body style.
• AMG E 53 Hybrid Wagon: This is the best-value trim if you want the most distinctive version of the lineup. It combines the wagon body style, strong utility, impressive technology, and the plug-in hybrid AMG powertrain, making it the most compelling pick for buyers who want something uncommon and genuinely quick.

The safety package is not standard across the lineup, so if advanced driver assistance matters to you, make sure the car you’re considering has the right package equipped.

Is now a good time to buy a used 2026 Mercedes-Benz E-Class?

This looks like a moderate, selective-buyer market, so you can shop with some leverage if you’re patient and focused.

• Deal availability: 35.1% of listings are priced as good or great deals.
• Inventory: There are 638 listings available.
• Clean inventory: 97.3% of listings are accident-free.

Is the 2026 Mercedes-Benz E-Class safe?

The 2026 Mercedes-Benz E-Class does not have published NHTSA or IIHS safety ratings yet.

It earns an 8/10 safety score from our experts.

The standard safety equipment includes high-beam assist, forward-collision warning, automatic emergency braking, blind-spot monitors, an exit warning system, a surround-view camera system, front and rear parking sensors, semi-autonomous self-parking, Pre-Safe forward-collision preparation, Pre-Safe Sound, and SOS emergency call service. The optional Driver Assistance Package adds adaptive cruise control, active blind-spot monitoring, active intersection assist, active emergency stop assist, active lane-change assist, active lane-keep assist, active steering assist, automatic lane change capability, evasive steering assist, congestion emergency braking, and rear- and side-impact Pre-Safe preparation.

The main caveat is that advanced safety features are not standard, so you’ll want to verify package content carefully on any used example you’re considering.

Should I buy a 2026 Mercedes-Benz E-Class or consider a different year?

If you're weighing the 2026 against nearby model years, here's how to think about it:

• 35.1% of listings are priced as good or great deals.
• Accident-free inventory is excellent at 97.3% — clean inventory, standard diligence applies.
• The 2026 model stands out for keeping the wagon body style alive while adding a standard biometric fingerprint scanner and debuting the AMG E 53 Hybrid wagon.

The bottom line:

If you want the newest E-Class with the wagon body style, the AMG E 53 Hybrid wagon, and the latest tech touches, the 2026 is the one to target. If you’re more price-sensitive, you can shop the market carefully and look for the right equipment mix, especially because the lineup’s appeal depends heavily on trim and option content.

These recommendations are based on CarGurus' proprietary market data from September 15, 2026, CarGurus experts' opinions, and generative AI.