Used 2021 Mercedes-Benz GLS 580 4MATIC for SaleNationwide
45 vehicles found
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- White
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 56,891
- Stock #:
- A360533B
- VIN:
- 4JGFF8GE6MA408488
2021 Mercedes-Benz GLS
580 4MATIC
56,891 mi
Sarasota, FL
Good Deal
$45,899
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Lunar Blue Metallic
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 34,575
- Stock #:
- B12404SA
- VIN:
- 4JGFF8GEXMA381022
2021 Mercedes-Benz GLS
580 4MATIC
34,575 mi
Atlanta, GA
Great Deal
$44,116
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 77,240
- Stock #:
- 9441641B
- VIN:
- 4JGFF8GE0MA451532
Price drop
-$3,700
2021 Mercedes-Benz GLS
580 4MATIC
77,240 mi
Tampa, FL
Great Deal
$39,022
$37,407
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 77,676
- Stock #:
- B70307A
- VIN:
- 4JGFF8GE3MA533044
2021 Mercedes-Benz GLS
580 4MATIC
77,676 mi
Ferriday, LA
Fair Deal
$43,093
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Gray (Selenite Grey Metallic)
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 67,564
- Stock #:
- R421743
- VIN:
- 4JGFF8GE6MA421743
Price drop
-$1,000
2021 Mercedes-Benz GLS
580 4MATIC
67,564 mi
Costa Mesa, CA
Good Deal
$42,229
$41,229
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Cavansite Blue Metallic
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Almond Leather
- Transmission:
- 9-Speed Automatic
- Mileage:
- 59,413
- Stock #:
- D03552
- VIN:
- 4JGFF8GE8MA403552
2021 Mercedes-Benz GLS
580 4MATIC
59,413 mi
Fletcher, NC
Fair Deal
$48,773
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Polar White
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 78,898
- Stock #:
- MA388127T
- VIN:
- 4JGFF8GE4MA388127
2021 Mercedes-Benz GLS
580 4MATIC
78,898 mi
Ridgeland, MS
Good Deal
$42,887
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Gray (Selenite Grey Metallic)
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 45,916
- Stock #:
- 36165A
- VIN:
- 4JGFF8GE0MA497510
2021 Mercedes-Benz GLS
580 4MATIC
45,916 mi
Oak Lawn, IL
Fair Deal
$50,379
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Obsidian Black Metallic
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 47,749
- Stock #:
- SM6569
- VIN:
- 4JGFF8GE0MA441504
2021 Mercedes-Benz GLS
580 4MATIC
47,749 mi
Eugene, OR
Great Deal
$45,650
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Silver
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 40,815
- Stock #:
- 18037
- VIN:
- 4JGFF8GE9MA396191
Price drop
-$4,000
2021 Mercedes-Benz GLS
580 4MATIC
40,815 mi
Columbia, SC
Good Deal
$53,399
$49,399
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Polar White
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 54,392
- Stock #:
- MA414656
- VIN:
- 4JGFF8GE9MA414656
New arrival
2021 Mercedes-Benz GLS
580 4MATIC
54,392 mi
Houston, TX
Good Deal
$45,223
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 24,815
- Stock #:
- ZZ390585
- VIN:
- 4JGFF8GE0MA390585
New arrival
2021 Mercedes-Benz GLS
580 4MATIC
24,815 mi
Daytona Beach, FL
Good Deal
$57,695
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Polar White
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 83,817
- Stock #:
- MA543144
- VIN:
- 4JGFF8GE2MA543144
Price drop
-$869
2021 Mercedes-Benz GLS
580 4MATIC
83,817 mi
Bellevue, WA
Good Deal
$40,861
$39,992
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Diamond White Metallic
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 59,607
- Stock #:
- 26041
- VIN:
- 4JGFF8GEXMA404816
2021 Mercedes-Benz GLS
580 4MATIC
59,607 mi
Fresno, CA
Fair Deal
$46,784
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 85,193
- Stock #:
- KP10587
- VIN:
- 4JGFF8GE6MA528243
2021 Mercedes-Benz GLS
580 4MATIC
85,193 mi
Chesapeake, VA
Good Deal
$40,004
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- White
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 75,618
- Stock #:
- MU443211
- VIN:
- 4JGFF8GE6MA443211
2021 Mercedes-Benz GLS
580 4MATIC
75,618 mi
Milford, CT
Fair Deal
$43,293
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Beige)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 84,824
- Stock #:
- 18989
- VIN:
- 4JGFF8GEXMA473263
2021 Mercedes-Benz GLS
580 4MATIC
84,824 mi
Lemont, IL
Good Deal
$38,278
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Polar White
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 85,318
- Stock #:
- AG0189A
- VIN:
- 4JGFF8GE1MA408849
2021 Mercedes-Benz GLS
580 4MATIC
85,318 mi
Kansas City, MO
Good Deal
$40,100
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- designo Diamond White Metallic
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 31,478
- Stock #:
- MA529305
- VIN:
- 4JGFF8GE7MA529305
New arrival
2021 Mercedes-Benz GLS
580 4MATIC
31,478 mi
Manchester, NH
Good Deal
$53,086
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- designo Diamond White Bright
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 47,958
- Stock #:
- U31806T
- VIN:
- 4JGFF8GEXMA487440
New arrival
2021 Mercedes-Benz GLS
580 4MATIC
47,958 mi
Torrance, CA
Great Deal
$44,872
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Lunar Blue Metallic
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 60,621
- Stock #:
- S19786A
- VIN:
- 4JGFF8GE3MA386739
2021 Mercedes-Benz GLS
580 4MATIC
60,621 mi
Newton, NC
Fair Deal
$46,999
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 47,723
- Stock #:
- PMA563463
- VIN:
- 4JGFF8GE8MA563463
2021 Mercedes-Benz GLS
580 4MATIC
47,723 mi
National City, CA
Good Deal
$46,973
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Cardinal Red Metallic
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 76,212
- Stock #:
- MA487198T
- VIN:
- 4JGFF8GE7MA487198
New arrival
2021 Mercedes-Benz GLS
580 4MATIC
76,212 mi
Omaha, NE
Fair Deal
$44,892
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Selenite Gray Metallic
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 66,334
- Stock #:
- STK396340
- VIN:
- 4JGFF8GE0MA396340
2021 Mercedes-Benz GLS
580 4MATIC
66,334 mi
Westfield, IN
Fair Deal
$44,995
FAQs
How much does the Mercedes-Benz GLS 580 4MATIC cost?
The average Mercedes-Benz GLS 580 4MATIC costs about $47,829.68. The average price has decreased by -7.8% since last year. The 335 for sale on CarGurus range from $31,382 to $123,599 in price.
How many Mercedes-Benz GLS 580 4MATIC vehicles have no reported accidents or damage?
300 out of 335 for sale have no reported accidents or damage.
What is the fuel economy of the Mercedes-Benz GLS 580 4MATIC?
Depending on the engine and options, the Mercedes-Benz GLS 580 4MATIC gets between 16 and 18 MPG/MPGe.
What fuel types are available?
Gasoline engines are available.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
Relevant articles
CarGurus Editorial Team
The Best Large SUVs for Gas Mileage in 2026
Large SUVs and great gas mileage don't tend to go hand-in-hand. That said, some models are more impressive than others. Here are our favourites, including the BMW X7 and Chevrolet Tahoe.
Matt Smith
The Best New Cars for Old Money Style in 2026
Whether you’re looking for something classic and timeless or you just want a nice vehicle that doesn’t project extreme affluence, there are a lot of new vehicles on the market today that feel luxurious, look elegant, yet don’t attract much attention.
Kirk Bell
2027 Mercedes-Maybach GLS 680 Pricing, Specs, and Release Date
The Mercedes-Benz GLS lineup gets a refresh for 2027 which includes the Mercedes-Maybach version. Its name changes from GLS 600 to GLS 680 in the process, and the update includes design changes, more power, updated connected technology, and updated ADAS.
Mercedes-Benz GLS 580 4MATIC in CaliforniaMercedes-Benz GLS 580 4MATIC in IllinoisMercedes-Benz GLS 580 4MATIC in MichiganMercedes-Benz GLS 580 4MATIC in MissouriMercedes-Benz GLS 580 4MATIC in New MexicoMercedes-Benz GLS 580 4MATIC in OhioMercedes-Benz GLS 580 4MATIC in PennsylvaniaMercedes-Benz GLS 580 4MATIC in TennesseeMercedes-Benz GLS 580 4MATIC in UtahMercedes-Benz GLS 580 4MATIC in Washington
All Used CarsManual Transmission CarsLuxury CarsCars with Red InteriorCheap Manual CarsHybrid CarsSports CarsElectric SUVsCheap TrucksSmall CarsThird Row SUVsThree Quarter Ton TrucksLifted TrucksManual Transmission TrucksDiesel TrucksHybrid SUVsDually TrucksOne Ton TrucksCheap SUVsLifted Ford Trucks4x4 TrucksWork TrucksAWD SUVsFord TrucksChevrolet TrucksToyota TrucksTrucks Under $10,000Cars Under $15,000Sports Cars Under $20,000Trucks Under $20,000Used Sedans for Sale with Low MileageUsed SUVs / Crossovers for Sale with Low MileageUsed Hatchbacks for Sale with Low MileageUsed Convertibles for Sale with Low MileageUsed Vans for Sale with Low MileageUsed Minivans for Sale with Low MileageUsed Pickup Trucks for Sale with Low MileageUsed Coupes for Sale with Low MileageUsed Wagons for Sale with Low Mileage
