Used 2021 Lexus RX Hybrid 450h AWD for Sale Nationwide
37 results
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- White
- Transmission:
- Automatic
- Mileage:
- 75,166
- Stock #:
- 27447
- VIN:
- 2T2HGMDA1MC063205
2021 Lexus RX Hybrid
450h AWD
75,166 mi
Escondido, CA
Fair Deal
$37,584
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 32,935
- Stock #:
- CJ41596A
- VIN:
- 2T2HGMDA2MC068123
Price drop
-$5,062
2021 Lexus RX Hybrid
450h AWD
32,935 mi
Lutz, FL
Great Deal
$45,357
$40,295
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 97,843
- Stock #:
- L19093T
- VIN:
- 2T2HGMDA1MC057081
2021 Lexus RX Hybrid
450h AWD
97,843 mi
Ramsey, NJ
Good Deal
$32,253
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 55,059
- Stock #:
- MVP11549
- VIN:
- 2T2HGMDA8MC066974
2021 Lexus RX Hybrid
450h AWD
55,059 mi
Manassas, VA
Good Deal
$40,254
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 100,649
- Stock #:
- TC135877A
- VIN:
- 2T2HGMDA4MC057835
Price drop
-$4,248
2021 Lexus RX Hybrid
450h AWD
100,649 mi
Santa Monica, CA
Great Deal
$34,328
$30,080
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 92,688
- Stock #:
- LC139472A
- VIN:
- 2T2HGMDA0MC071375
2021 Lexus RX Hybrid
450h AWD
92,688 mi
Colorado Springs, CO
Fair Deal
$34,668
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- 6-Speed CVT
- Mileage:
- 47,033
- Stock #:
- 6544
- VIN:
- 2T2HGMDA2MC063648
2021 Lexus RX Hybrid
450h AWD
47,033 mi
Lees Summit, MO
Good Deal
$41,990
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 101,036
- Stock #:
- JM057731
- VIN:
- 2T2HGMDA3MC057731
2021 Lexus RX Hybrid
450h AWD
101,036 mi
Nashville, TN
Great Deal
$30,604
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Matador Red Mica
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- White (Parchment)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 25,713
- Stock #:
- 2065555
- VIN:
- 2T2HGMDA5MC065555
2021 Lexus RX Hybrid
450h AWD
25,713 mi
Reno, NV
Good Deal
$45,244
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 70,368
- Stock #:
- AMD26111B
- VIN:
- 2T2HGMDA3MC062685
2021 Lexus RX Hybrid
450h AWD
70,368 mi
Portland, OR
Fair Deal
$39,245
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Gray
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 58,090
- Stock #:
- C118329A
- VIN:
- 2T2JGMDA4MC070084
2021 Lexus RX Hybrid
450h AWD
58,090 mi
Sarasota, FL
Fair Deal
$42,083
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Gray Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Birch
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 58,475
- Stock #:
- 9751
- VIN:
- 2T2HGMDA5MC059870
2021 Lexus RX Hybrid
450h AWD
58,475 mi
Terryville, CT
Fair Deal
$42,108
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Brown (Beige Metallic)
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- White (Parchment)
- Transmission:
- Automatic
- Mileage:
- 95,775
- Stock #:
- MC063359M
- VIN:
- 2T2HGMDA6MC063359
2021 Lexus RX Hybrid
450h AWD
95,775 mi
Medford, OR
Good Deal
$33,573
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 51,353
- Stock #:
- T059712P
- VIN:
- 2T2JGMDA7MC059712
2021 Lexus RX Hybrid
450h AWD
51,353 mi
Suitland, MD
Fair Deal
$42,800
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black (Obsidian)
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black w/Striated Black Trim
- Transmission:
- Automatic
- Mileage:
- 82,601
- Stock #:
- 10101
- VIN:
- 2T2HGMDA2MC069739
2021 Lexus RX Hybrid
450h AWD
82,601 mi
Bountiful, UT
Good Deal
$34,450
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- White (Parchment)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 75,370
- Stock #:
- MC062768A
- VIN:
- 2T2HGMDA7MC062768
New arrival
2021 Lexus RX Hybrid
450h AWD
75,370 mi
Arlington, TX
Fair Deal
$38,995
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 43,784
- Stock #:
- LIT063598
- VIN:
- 2T2HGMDA2MC063598
2021 Lexus RX Hybrid
450h AWD
43,784 mi
Indianapolis, IN
Fair Deal
$44,300
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- White (Parchment)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 38,813
- Stock #:
- 88439A
- VIN:
- 2T2HGMDAXMC068225
2021 Lexus RX Hybrid
450h AWD
38,813 mi
Escondido, CA
Fair Deal
$42,880
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 52,011
- Stock #:
- MC057648
- VIN:
- 2T2HGMDA5MC057648
2021 Lexus RX Hybrid
450h AWD
52,011 mi
Fort Myers, FL
Great Deal
$38,394
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- White (Parchment)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 48,431
- Stock #:
- BMC065951
- VIN:
- 2T2HGMDA2MC065951
New arrival
2021 Lexus RX Hybrid
450h AWD
48,431 mi
Plano, TX
Fair Deal
$44,225
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Gray
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Brown (Tan)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 78,040
- Stock #:
- YMC062341
- VIN:
- 2T2JGMDA2MC062341
New arrival
2021 Lexus RX Hybrid
450h AWD
78,040 mi
Denver, CO
Fair Deal
$38,098
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- White (Parchment)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 68,506
- Stock #:
- S082597A
- VIN:
- 2T2JGMDA5MC064102
2021 Lexus RX Hybrid
450h AWD
68,506 mi
Louisville, KY
Fair Deal
$41,000
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Gray
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 84,187
- Stock #:
- 28875420
- VIN:
- 2T2HGMDA9MC061251
2021 Lexus RX Hybrid
450h AWD
84,187 mi
Escondido, CA
Good Deal
$34,998
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Glazed Caramel
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 79,011
- Stock #:
- M4086PS
- VIN:
- 2T2HGMDA8MC063654
2021 Lexus RX Hybrid
450h AWD
79,011 mi
Annapolis, MD
Fair Deal
$36,970
5.0 Overall rating
Filter by rating
David D
Reviewed a 2021 Lexus 450h AWD on Aug 25, 2025
I think it’s the most enjoyable car I’ve ever driven in my 66 years of driving
Is this review helpful?
FAQs
How much does the Lexus RX Hybrid 450h AWD cost?
The average Lexus RX Hybrid 450h AWD costs about $39,608.37. The average price has increased by 0.8% since last year. The 425 for sale on CarGurus range from $5,750 to $54,000 in price.
How many Lexus RX Hybrid 450h AWD vehicles have no reported accidents or damage?
268 out of 425 for sale have no reported accidents or damage.
What is the fuel economy of the Lexus RX Hybrid 450h AWD?
Depending on the engine and options, the Lexus RX Hybrid 450h AWD gets between 29 and 29 MPG (or EV battery range).
What fuel types are available?
Hybrid engines are available.
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