Used 2021 Lexus RX Hybrid 450h AWD for SaleNationwide
53 vehicles found
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Birch
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 74,813
- Stock #:
- GU1026
- VIN:
- 2T2HGMDA3MC063626
2021 Lexus RX Hybrid
450h AWD
74,813 mi
Brooklyn, NY
Good Deal
$34,163
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Birch
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 75,046
- Stock #:
- P9643
- VIN:
- 2T2HGMDA2MC062984
2021 Lexus RX Hybrid
450h AWD
75,046 mi
Albany, NY
Good Deal
$36,125
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 61,260
- Stock #:
- 266079A
- VIN:
- 2T2HGMDA3MC066106
New arrival
2021 Lexus RX Hybrid
450h AWD
61,260 mi
Fort Collins, CO
Fair Deal
$39,990
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 69,094
- Stock #:
- T0514
- VIN:
- 2T2HGMDA8MC069633
2021 Lexus RX Hybrid
450h AWD
69,094 mi
Fort Collins, CO
Fair Deal
$38,990
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Brown (Tan)
- Transmission:
- Automatic
- Mileage:
- 52,804
- Stock #:
- CMC068760
- VIN:
- 2T2HGMDAXMC068760
New arrival
2021 Lexus RX Hybrid
450h AWD
52,804 mi
Englewood, CO
Good Deal
$39,397
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- White (Parchment)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 43,886
- Stock #:
- U071130
- VIN:
- 2T2HGMDA3MC071130
2021 Lexus RX Hybrid
450h AWD
43,886 mi
Butler, NJ
Good Deal
$40,878
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Birch
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 57,943
- Stock #:
- MC070594
- VIN:
- 2T2HGMDA7MC070594
New arrival
2021 Lexus RX Hybrid
450h AWD
57,943 mi
Portland, OR
Fair Deal
$42,099
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Birch
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 41,084
- Stock #:
- MC071411P
- VIN:
- 2T2HGMDA0MC071411
New arrival
2021 Lexus RX Hybrid
450h AWD
41,084 mi
Richardson, TX
Fair Deal
$41,212
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black (Obsidian)
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 85,739
- Stock #:
- L321062A
- VIN:
- 2T2JGMDA4MC069503
New arrival
2021 Lexus RX Hybrid
450h AWD
85,739 mi
Saint Paul, MN
Fair Deal
$37,987
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- White (Parchment)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 23,338
- Stock #:
- D2854A
- VIN:
- 2T2HGMDA5MC064812
New arrival
2021 Lexus RX Hybrid
450h AWD
23,338 mi
Peoria, AZ
Fair Deal
$46,587
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 49,253
- Stock #:
- G50116
- VIN:
- 2T2HGMDAXMC067902
2021 Lexus RX Hybrid
450h AWD
49,253 mi
Savannah, TN
Fair Deal
$42,933
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- White (Parchment)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 36,747
- Stock #:
- C065866T
- VIN:
- 2T2HGMDA0MC065866
2021 Lexus RX Hybrid
450h AWD
36,747 mi
Austin, TX
Fair Deal
$45,205
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 79,350
- Stock #:
- MC067140
- VIN:
- 2T2HGMDA8MC067140
2021 Lexus RX Hybrid
450h AWD
79,350 mi
Albuquerque, NM
Good Deal
$36,188
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Mica
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Birch
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 100,573
- Stock #:
- A065888
- VIN:
- 2T2HGMDAXMC065888
2021 Lexus RX Hybrid
450h AWD
100,573 mi
Bensenville, IL
Good Deal
$34,004
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 69,023
- Stock #:
- 26387
- VIN:
- 2T2HGMDA1MC069134
2021 Lexus RX Hybrid
450h AWD
69,023 mi
Franktown, CO
Good Deal
$37,950
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 51,056
- Stock #:
- U2200475
- VIN:
- 2T2HGMDA9MC065431
2021 Lexus RX Hybrid
450h AWD
51,056 mi
Lowell, MA
Fair Deal
$41,279
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- White (Parchment)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 65,998
- Stock #:
- KT2914
- VIN:
- 2T2HGMDA8MC071110
2021 Lexus RX Hybrid
450h AWD
65,998 mi
Indio, CA
Good Deal
$38,677
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Matador Red Mica
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 73,886
- Stock #:
- 627332A
- VIN:
- 2T2HGMDA4MC067037
2021 Lexus RX Hybrid
450h AWD
73,886 mi
Greenwich, CT
Great Deal
$35,695
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 50,662
- Stock #:
- MC070592P
- VIN:
- 2T2HGMDA3MC070592
Price drop
-$999
2021 Lexus RX Hybrid
450h AWD
50,662 mi
Torrance, CA
Good Deal
$40,997
$40,083
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 74,134
- Stock #:
- 54L1339P
- VIN:
- 2T2HGMDA9MC069947
2021 Lexus RX Hybrid
450h AWD
74,134 mi
Wichita, KS
Fair Deal
$40,593
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Birch
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 34,888
- Stock #:
- MC062837
- VIN:
- 2T2HGMDA0MC062837
2021 Lexus RX Hybrid
450h AWD
34,888 mi
Parker, CO
Fair Deal
$45,199
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Gray
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Brown
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 52,876
- Stock #:
- B100290
- VIN:
- 2T2JGMDA7MC058043
2021 Lexus RX Hybrid
450h AWD
52,876 mi
Elkridge, MD
Fair Deal
$42,794
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Birch
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 80,356
- Stock #:
- M1246
- VIN:
- 2T2HGMDA1MC062815
New arrival
2021 Lexus RX Hybrid
450h AWD
80,356 mi
Henderson, NV
Good Deal
$36,494
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 61,901
- Stock #:
- TMC058104
- VIN:
- 2T2HGMDA3MC058104
2021 Lexus RX Hybrid
450h AWD
61,901 mi
Palm Springs, CA
Fair Deal
$40,073
5.0 Overall rating
Filter by rating
David D
Reviewed a 2021 Lexus 450h AWD on Aug 25, 2025
I think it’s the most enjoyable car I’ve ever driven in my 66 years of driving
Is this review helpful?
FAQs
How much does the Lexus RX Hybrid 450h AWD cost?
The average Lexus RX Hybrid 450h AWD costs about $39,729.99. The average price has increased by 0.7% since last year. The 451 for sale on CarGurus range from $6,294 to $54,041 in price.
How many Lexus RX Hybrid 450h AWD vehicles have no reported accidents or damage?
305 out of 451 for sale have no reported accidents or damage.
What is the fuel economy of the Lexus RX Hybrid 450h AWD?
Depending on the engine and options, the Lexus RX Hybrid 450h AWD gets between 29 and 29 MPG/MPGe.
What fuel types are available?
Hybrid engines are available.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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