Used 2021 Lexus RX Hybrid 450h AWD for SaleNationwide
45 vehicles found
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Green Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Glazed Caramel
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 37,833
- Stock #:
- D10423A
- VIN:
- 2T2HGMDA0MC072039
2021 Lexus RX Hybrid
450h AWD
37,833 mi
Shakopee, MN
Good Deal
$43,944
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Birch
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 74,745
- Stock #:
- TMC068951
- VIN:
- 2T2HGMDA6MC068951
New arrival
2021 Lexus RX Hybrid
450h AWD
74,745 mi
Huntersville, NC
Good Deal
$38,777
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 38,886
- Stock #:
- TC059038
- VIN:
- 2T2HGMDAXMC059038
New arrival
2021 Lexus RX Hybrid
450h AWD
38,886 mi
Rockville, MD
Good Deal
$43,297
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 47,453
- Stock #:
- M666146A
- VIN:
- 2T2HGMDAXMC071061
2021 Lexus RX Hybrid
450h AWD
47,453 mi
Somerville, MA
Good Deal
$41,297
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Birch
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 52,630
- Stock #:
- P8798G
- VIN:
- 2T2HGMDA4MC067264
New arrival
2021 Lexus RX Hybrid
450h AWD
52,630 mi
Norwell, MA
Fair Deal
$41,539
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black (Obsidian)
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black w/Striated Black Trim
- Transmission:
- Automatic
- Mileage:
- 82,601
- Stock #:
- 10101
- VIN:
- 2T2HGMDA2MC069739
2021 Lexus RX Hybrid
450h AWD
82,601 mi
Bountiful, UT
Great Deal
$34,449
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Nightfall Mica
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Birch
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 51,030
- Stock #:
- 260439B
- VIN:
- 2T2HGMDA9MC065798
2021 Lexus RX Hybrid
450h AWD
51,030 mi
Fort Pierce, FL
Fair Deal
$43,427
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- White (Parchment)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 73,662
- Stock #:
- P7601
- VIN:
- 2T2HGMDA2MC062161
2021 Lexus RX Hybrid
450h AWD
73,662 mi
Covington, LA
Fair Deal
$38,647
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- White (Parchment)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 55,857
- Stock #:
- DP12229A
- VIN:
- 2T2HGMDA9MC062223
2021 Lexus RX Hybrid
450h AWD
55,857 mi
Durham, NC
Fair Deal
$43,887
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 50,200
- Stock #:
- PLGPMC071328
- VIN:
- 2T2HGMDA2MC071328
2021 Lexus RX Hybrid
450h AWD
50,200 mi
Grapevine, TX
Good Deal
$41,791
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 50,627
- Stock #:
- 70140712
- VIN:
- 2T2HGMDA1MC060496
2021 Lexus RX Hybrid
450h AWD
50,627 mi
Murrieta, CA
Fair Deal
$42,998
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 107,259
- Stock #:
- 54982A
- VIN:
- 2T2HGMDA4MC071010
Preparing for a close up...
Photos coming soon
2021 Lexus RX Hybrid
450h AWD
107,259 mi
Concord, CA
Fair Deal
$34,083
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 63,328
- Stock #:
- MC064160
- VIN:
- 2T2HGMDAXMC064160
2021 Lexus RX Hybrid
450h AWD
63,328 mi
Mt Laurel, NJ
Good Deal
$39,748
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 32,935
- Stock #:
- P8784
- VIN:
- 2T2HGMDA2MC068123
2021 Lexus RX Hybrid
450h AWD
32,935 mi
Beavercreek, OH
Fair Deal
$45,438
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black (Obsidian)
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 46,658
- Stock #:
- RU067305
- VIN:
- 2T2HGMDA3MC067305
New arrival
2021 Lexus RX Hybrid
450h AWD
46,658 mi
Wilmington, DE
Good Deal
$41,800
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Birch
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 74,813
- Stock #:
- GU1026
- VIN:
- 2T2HGMDA3MC063626
2021 Lexus RX Hybrid
450h AWD
74,813 mi
Brooklyn, NY
Fair Deal
$36,663
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 86,862
- Stock #:
- B36100A
- VIN:
- 2T2HGMDA1MC069702
2021 Lexus RX Hybrid
450h AWD
86,862 mi
West Springfield, MA
Fair Deal
$36,182
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- 6-Speed CVT
- Mileage:
- 47,033
- Stock #:
- 6544
- VIN:
- 2T2HGMDA2MC063648
2021 Lexus RX Hybrid
450h AWD
47,033 mi
Lees Summit, MO
Good Deal
$41,290
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 68,934
- Stock #:
- MC069134
- VIN:
- 2T2HGMDA1MC069134
New arrival
2021 Lexus RX Hybrid
450h AWD
68,934 mi
Dallas, TX
Fair Deal
$39,958
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- White (Parchment)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 76,725
- Stock #:
- P12420
- VIN:
- 2T2JGMDA6MC072144
2021 Lexus RX Hybrid
450h AWD
76,725 mi
Raleigh, NC
Fair Deal
$42,379
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 37,699
- Stock #:
- 28773251
- VIN:
- 2T2HGMDA4MC057673
2021 Lexus RX Hybrid
450h AWD
37,699 mi
El Cajon, CA
Good Deal
$41,998
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Gray
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 88,798
- Stock #:
- SLLTMC071859
- VIN:
- 2T2HGMDA0MC071859
New arrival
2021 Lexus RX Hybrid
450h AWD
88,798 mi
Lakewood, CO
Good Deal
$36,000
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Birch
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 95,109
- Stock #:
- 43019A
- VIN:
- 2T2HGMDA7MC063306
Preparing for a close up...
Photos coming soon
New arrival
2021 Lexus RX Hybrid
450h AWD
95,109 mi
Raleigh, NC
Fair Deal
$36,879
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- White
- Transmission:
- Automatic
- Mileage:
- 75,166
- Stock #:
- 27447
- VIN:
- 2T2HGMDA1MC063205
2021 Lexus RX Hybrid
450h AWD
75,166 mi
Escondido, CA
Fair Deal
$37,584
5.0 Overall rating
Filter by rating
David D
Reviewed a 2021 Lexus 450h AWD on Aug 25, 2025
I think it’s the most enjoyable car I’ve ever driven in my 66 years of driving
Is this review helpful?
FAQs
How much does the Lexus RX Hybrid 450h AWD cost?
The average Lexus RX Hybrid 450h AWD costs about $40,622.09. The average price has increased by 2.1% since last year. The 458 for sale on CarGurus range from $6,198 to $52,995 in price.
How many Lexus RX Hybrid 450h AWD vehicles have no reported accidents or damage?
293 out of 458 for sale have no reported accidents or damage.
What is the fuel economy of the Lexus RX Hybrid 450h AWD?
Depending on the engine and options, the Lexus RX Hybrid 450h AWD gets between 29 and 29 MPG (or EV battery range).
What fuel types are available?
Hybrid engines are available.
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