Used 2021 Lexus NX for Sale nearSaint Louis, MO

How much does the 2021 Lexus NX cost?

Prices have softened 1.63% compared to this time last year, making it a favorable time to shop this model year.

There are 947 listings available, which suggests a healthy amount of inventory to compare.

Is the 2021 Lexus NX a good car?

Yes — the 2021 Lexus NX earns a 4.8/5 user rating and a 7/10 expert rating. The standout strength is Cost effectiveness at 8/10.

Owners consistently praise its stylish design, safety features, and comfortable interior. The expert review also points to its good looks, high-quality cabin, and quiet ride as recurring strengths.

The trade-offs are clear: the interior materials can feel cheap, handling is poor, and the back seat is cramped. That makes it a better fit if you value a premium-feeling compact SUV for daily driving more than rear-seat space or sharp dynamics.

With 37.4% of listings marked as good or great deals, there’s still room to shop selectively.

Is the 2021 Lexus NX reliable?

Owners rate it 4.8/5, a strong signal of long-term satisfaction.

User feedback points to a dependable ownership experience, with owners highlighting the NX’s strong reputation and trouble-free feel. The expert review also reinforces that sense of durability by describing the NX as a traditional Lexus with historically strong reliability.

Lexus also includes a 10-year subscription to its maintenance-alert service, which can help you stay ahead of scheduled service needs.

For used buyers, the main long-term risk is less about outright mechanical weakness and more about finding an example that has been maintained well and not worn down by age or neglect.

What should I look for when buying a used 2021 Lexus NX?

At 74.4% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.

You should run a vehicle history report before you commit, then prioritize a pre-purchase inspection if the listing has any accident or repair history. Pay close attention to cabin condition, because the NX’s interior quality and comfort are major selling points, and worn materials or neglected maintenance can undercut that appeal.

Key things to evaluate:

• Trim level: The NX 300 comes in base and Luxury trims, while the NX 300 F Sport adds a sportier look with a honeycomb grille, triple-beam LED headlights, 18-inch wheels, and quilted NuLuxe sport seats. The base trim is the value play if you want the NX experience without paying for appearance upgrades.
• Powertrain: The NX 300 and NX 300 F Sport use a turbocharged 2.0-liter four-cylinder engine with 235 horsepower and 258 pound-feet of torque. Front-wheel drive is standard, and all-wheel drive is available on every trim level.
• Safety package: Lexus Safety System+ 2.0 is standard, with a rearview camera, lane-departure warning, lane-keep assist, traffic-sign recognition, automatic high beams, forward-collision warning, automatic emergency braking, pedestrian detection, and adaptive cruise control. Blind-spot monitoring and rear cross-traffic alert are standard too.
• Infotainment: An 8-inch touchscreen is standard, and a 10.3-inch screen is available with the Navigation package. Apple CarPlay and Android Auto are standard, and the Navigation package adds predictive traffic information, HomeLink, and Lexus Enform Destination Assist.
• Fuel efficiency: The FWD model gets 22 mpg in the city, 28 mpg on the highway, and 25 mpg combined. AWD versions return 22 mpg city, 28 mpg highway, and 24 mpg combined.

Which 2021 Lexus NX trim should I buy?

The 2021 Lexus NX is offered in 3 trim levels: NX 300, NX 300 F Sport, and NX 300 Luxury.

Here's the short version:

• NX 300: This is the trim to start with if you want the NX’s core strengths at the lowest entry price. It gives you the standard turbocharged engine, standard safety tech, Apple CarPlay, Android Auto, and the NX’s comfortable, quiet character without paying for sport styling or luxury extras.
• NX 300 F Sport: Choose this if you want the most distinctive look and a more aggressive presentation. It adds the sportier exterior treatment, exclusive quilted NuLuxe sport seats, and available leather-and-wood trim, but it’s best for buyers who care more about style than added practicality.
• NX 300 Luxury: This is the trim to consider if you want the most upscale version of the gas NX. It’s the right pick for shoppers who value a more premium feel and are willing to pay more for it.

Lexus Safety System+ 2.0 is standard across the lineup, and blind-spot monitoring and rear cross-traffic alert are standard as well.

Is now a good time to buy a used 2021 Lexus NX?

This looks like a moderate, selective buyer’s market, so you can shop carefully and still find worthwhile listings.

• Deal availability: 37.4% of listings are priced as good or great deals.
• Inventory: There are 947 listings available.
• Price trend: Prices have softened 1.63% compared with last year.
• Clean inventory: 74.4% of listings are accident-free.

If you find a listing below $27,460, that's toward the low end of the year-round range and worth acting on quickly.

What is the 2021 Lexus NX's resale value?

The current average of $28,778 sits slightly below last year's $29,255.

That softer pricing can help you buy at a more favorable point in the cycle, but it also means future resale gains may be more limited if the market stays soft. For a seller, the key takeaway is that the NX still has recognizable brand appeal, but pricing discipline matters if you want to stay competitive.

Its strong owner satisfaction should help support demand when you eventually sell. Vehicles with strong owner satisfaction ratings, like this model year's 4.8/5, tend to retain buyer demand, which supports resale value over time.

Is the 2021 Lexus NX safe?

The Lexus NX earns top "Good" scores in all IIHS crash tests and a five-star overall safety rating from NHTSA.

It earns a 7/10 safety score from our experts.

Lexus Safety System+ 2.0 is standard, and it includes a rearview camera, lane-departure warning, lane-keep assist, traffic-sign recognition, automatic high beams, forward-collision warning, automatic emergency braking, pedestrian detection, and adaptive cruise control. Blind-spot monitoring and rear cross-traffic alert are standard too.

Lexus Enform Safety Connect is also included, with emergency assistance, roadside assistance, automatic collision notification, and stolen-vehicle notification. Park assist, a surround-view camera system, and adaptive headlights are optional extras.

Should I buy a 2021 Lexus NX or consider a different year?

If you're weighing the 2021 against nearby model years, here's how to think about it:

Choose the 2021 if:

• 37.4% of listings are priced as good or great deals.
• At 74.4% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
• Price trend: Prices have softened 1.63% compared with last year.
• Owners rate it 4.8/5 — a strong satisfaction signal.
• It keeps the familiar NX formula with strong safety equipment, a quiet cabin, and a comfortable ride.

Consider the 2022 if:

• At $35,513, the 2022 costs more than the current year's $28,778 average.
• The redesign brings a more modern, tech-forward cabin and a more dynamic overall feel.

The bottom line: If you want the lower price and the familiar NX strengths, the 2021 is the smarter buy. If you’re willing to spend more for a newer design and a more advanced feel, the 2022 is the better long-term choice. For price-sensitive shoppers, the 2021 offers the stronger value proposition right now.

These recommendations are based on CarGurus' proprietary market data from September 22, 2026, CarGurus experts' opinions, and generative AI.