The Chrysler Pacifica entered its second year of production in 2005, with an expanded model lineup. For this year, four trims levels were offered, including Base, Touring, Limited, and Signature Series.

The Base model is identical to last year's Pacifica, but the Touring and Limited trims get several features upgrades. The Signature Seires is special package. All Pacificas come standard with first and second row heated seats, power front seats, second row captain's chairs, adjustable pedals, dual-zone climate control, and full power accessories. Limited and Touring models include a 10-way power driver's seat, automatic climate control, a navigation system, and Chrysler's hands-free "UConnect" communication system.

All models are powered by a 3.5 liter DOHC V-6, which supplies 250 horsepower and 250 pound-feet of torque. All models use a four-speed automatic transmission. Drivers can expect mixed driving mileage around 20 mpg.