can you use e85 gas in a 2016 yukon denali

My GM Shop Service Manual, Revised January 2017 states: Recommended fuel premium unleaded gasoline with a posted octane rating of 91 or higher. Regular unleaded gasoline rated at 87 octane can be used but the vehicle's acceleration could be slightly reduced, and a slight audible knocking noise, commonly referred to as spark knock, might be heard as well, this will not cause significant damage to the engine, but should be avoided.

Only if you have a flexfuel engine rated for E85. Most engines should only use E10 or straight gas.