Used 2021 RAM 2500 for Sale nearRoanoke, VA
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2021
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 370 hp 6.7L I6 Diesel
- Exterior color:
- Pearl White
- Fuel type:
- Diesel
- Interior color:
- Lt Mountain Brown/Brown
- Transmission:
- 6-Speed Automatic
- Mileage:
- 84,955
- Stock #:
- 584212
- VIN:
- 3C6UR5GLXMG584212


Sponsored by Smart Chevrolet
2021 RAM 2500
Limited Longhorn Crew Cab 4WD
84,955 mi
$53,689
- Year:
- 2021
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 370 hp 6.7L I6 Diesel
- Exterior color:
- Gray (Granite Crystal Metallic Clearcoat)
- Fuel type:
- Diesel
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 88,675
- Stock #:
- 530298
- VIN:
- 3C6UR5NL3MG530298

Sponsored Listing
2021 RAM 2500
Laramie Mega Cab 4WD
88,675 mi
$53,736
- Year:
- 2022
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 370 hp 6.7L I6 Diesel
- Exterior color:
- Silver
- Fuel type:
- Diesel
- Transmission:
- Automatic
- Mileage:
- 62,531
- Stock #:
- T30402A
- VIN:
- 3C6UR5CL3NG298290

Sponsored Listing
2022 RAM 2500
Tradesman Crew Cab 4WD
62,531 mi
$39,788
- Year:
- 2021
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 370 hp 6.7L I6 Diesel
- Exterior color:
- White
- Fuel type:
- Diesel
- Interior color:
- Gray
- Transmission:
- 6-Speed Automatic
- Mileage:
- 81,615
- Stock #:
- 522476
- VIN:
- 3C6UR5DL3MG522476

2021 RAM 2500
Big Horn Crew Cab 4WD
81,615 mi
$40,687
- Year:
- 2022
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 370 hp 6.7L I6 Diesel
- Exterior color:
- White
- Fuel type:
- Diesel
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 44,012
- Stock #:
- U14333
- VIN:
- 3C6UR5DL2NG108798

2022 RAM 2500
Big Horn Crew Cab 4WD
44,012 mi
$47,277
- Year:
- 2020
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 370 hp 6.7L I6 Diesel
- Exterior color:
- Diamond Black Crystal Pearlcoat
- Fuel type:
- Diesel
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 103,209
- Stock #:
- 149159A
- VIN:
- 3C6UR5CLXLG149159

2020 RAM 2500
Tradesman Crew Cab 4WD
103,209 mi
$35,014
- Year:
- 2022
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 410 hp 6.4L V8
- Exterior color:
- Pearl White
- Fuel type:
- Gasoline
- Interior color:
- Light Mountain Brown/Mountain Brown
- Transmission:
- 8-Speed Automatic
- Mileage:
- 51,098
- Stock #:
- 217669C
- VIN:
- 3C6UR5GJ7NG217669

2022 RAM 2500
Limited Longhorn Crew Cab 4WD
51,098 mi
$49,770
- Year:
- 2020
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 370 hp 6.7L I6 Diesel
- Exterior color:
- White
- Fuel type:
- Diesel
- Interior color:
- Brown
- Transmission:
- 6-Speed Automatic
- Mileage:
- 105,189
- Stock #:
- 217399
- VIN:
- 3C6UR5PL6LG217399

2020 RAM 2500
Longhorn Mega Cab 4WD
105,189 mi
$48,962
- Year:
- 2021
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 410 hp 6.4L V8
- Exterior color:
- Silver
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- 8-Speed Automatic
- Mileage:
- 70,523
- Stock #:
- 682021
- VIN:
- 3C6UR5CJ5MG682021

2021 RAM 2500
Tradesman Crew Cab 4WD
70,523 mi
$33,962
- Year:
- 2021
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 370 hp 6.7L I6 Diesel
- Exterior color:
- Gray
- Fuel type:
- Diesel
- Transmission:
- 6-Speed Automatic
- Mileage:
- 54,248
- Stock #:
- 676362
- VIN:
- 3C6UR5FL5MG676362

2021 RAM 2500
Laramie Crew Cab 4WD
54,248 mi
$50,942
- Year:
- 2022
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 370 hp 6.7L I6 Diesel
- Exterior color:
- Patriot Blue Pearlcoat
- Fuel type:
- Diesel
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 40,341
- Stock #:
- T228615
- VIN:
- 3C6UR5FL2NG228615

2022 RAM 2500
Laramie Crew Cab 4WD
40,341 mi
$52,345
- Year:
- 2021
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 370 hp 6.7L I6 Diesel
- Exterior color:
- Pearl White
- Fuel type:
- Diesel
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 45,234
- Stock #:
- T9456A
- VIN:
- 3C6UR5SL8MG674689

2021 RAM 2500
Limited Crew Cab 4WD
45,234 mi
$58,257
- Year:
- 2022
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 410 hp 6.4L V8
- Exterior color:
- White
- Fuel type:
- Gasoline
- Interior color:
- Black (Charcoal)
- Transmission:
- Automatic
- Mileage:
- 123,912
- Stock #:
- 345396
- VIN:
- 3C6UR5DJ7NG345396

2022 RAM 2500
Big Horn Crew Cab 4WD
123,912 mi
$25,681
CarGurus Analysis:
2021 RAM 2500
With 457 currently listed for sale near Roanoke, VA and an average price of $31,987.00, 26.5% of 2021 RAM 2500s for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 RAM 2500 4.69 / 5 stars.
78.1% of 2021 RAM 2500 models on CarGurus are accident free.
- Year:
- 2022
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 410 hp 6.4L V8
- Exterior color:
- Diamond Black Crystal Pearlcoat
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 46,838
- Stock #:
- NG437101A
- VIN:
- 3C6UR5FJXNG437101

2022 RAM 2500
Laramie Crew Cab 4WD
46,838 mi
$48,266
- Year:
- 2022
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 410 hp 6.4L V8
- Exterior color:
- Bright White Clearcoat
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 103,409
- Stock #:
- Y1358
- VIN:
- 3C6UR5DJ6NG322319

2022 RAM 2500
Big Horn Crew Cab 4WD
103,409 mi
$32,284
- Year:
- 2021
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 370 hp 6.7L I6 Diesel
- Exterior color:
- Gray (Granite Crystal Metallic Clearcoat)
- Fuel type:
- Diesel
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 88,675
- Stock #:
- 530298
- VIN:
- 3C6UR5NL3MG530298

2021 RAM 2500
Laramie Mega Cab 4WD
88,675 mi
$53,736
- Year:
- 2022
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 410 hp 6.4L V8
- Exterior color:
- Bright White Clearcoat
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 31,243
- Stock #:
- 16Z0414
- VIN:
- 3C6TR5EJ4NG209379

2022 RAM 2500
Power Wagon Crew Cab 4WD
31,243 mi
$53,456
- Year:
- 2022
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 370 hp 6.7L I6 Diesel
- Exterior color:
- White
- Fuel type:
- Diesel
- Transmission:
- Automatic
- Mileage:
- 158,719
- Stock #:
- U4125
- VIN:
- 3C6UR5JL3NG161787

2022 RAM 2500
Big Horn Crew Cab LB 4WD
158,719 mi
$30,894
- Year:
- 2020
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 410 hp 6.4L V8
- Exterior color:
- Gray (Granite Crystal Metallic Clearcoat)
- Fuel type:
- Gasoline
- Interior color:
- Diesel Gray/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 90,148
- Stock #:
- 208304
- VIN:
- 3C6UR5CJ6LG208304
Preparing for a close up...
Photos coming soon
2020 RAM 2500
Tradesman Crew Cab 4WD
90,148 mi
$31,581
- Year:
- 2021
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 370 hp 6.7L I6 Diesel
- Exterior color:
- Gray (Granite Crystal Metallic Clearcoat)
- Fuel type:
- Diesel
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 122,523
- Stock #:
- 10464P
- VIN:
- 3C6UR5FL7MG630399

2021 RAM 2500
Laramie Crew Cab 4WD
122,523 mi
$37,605
- Year:
- 2020
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 370 hp 6.7L I6 Diesel
- Exterior color:
- Diamond Black
- Fuel type:
- Diesel
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 82,779
- Stock #:
- Y1283
- VIN:
- 3C6UR5CL7LG280761

2020 RAM 2500
Tradesman Crew Cab 4WD
82,779 mi
$37,884
- Year:
- 2021
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 370 hp 6.7L I6 Diesel
- Exterior color:
- White
- Fuel type:
- Diesel
- Interior color:
- Brown (Beige)
- Transmission:
- 6-Speed Automatic
- Mileage:
- 113,764
- Stock #:
- 677663
- VIN:
- 3C6UR5SL5MG677663

2021 RAM 2500
Limited Crew Cab 4WD
113,764 mi
$44,794
- Year:
- 2022
- Make:
- RAM
- Model:
- 2500
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 410 hp 6.4L V8
- Exterior color:
- Bright White Clearcoat
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 31,243
- Stock #:
- 16Z0414
- VIN:
- 3C6TR5EJ4NG209379

Sponsored Listing
2022 RAM 2500
Power Wagon Crew Cab 4WD
31,243 mi
$53,456
CarGurus Analysis: 2021 RAM 2500

Summary
With 457 currently listed for sale near Roanoke, VA and an average price of $31,987.00, 26.5% of 2021 RAM 2500s for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 RAM 2500 4.69 / 5 stars.
78.1% of 2021 RAM 2500 models on CarGurus are accident free.
Why it stands out
The 2021 RAM 2500 stands out as a heavy-duty pickup that blends serious capability with a more upscale feel than many buyers expect from a work truck. In the fifth generation, Ram put a huge focus on luxury and tech, and the truck adopted a more aerodynamic design, LED lighting, a stronger frame, new suspension, and a new transmission. It also gained a revised interior with better materials and available amenities, along with a standard trailer brake controller and a rotary gear selector.
For buyers who want a truck that can do real work, the 2021 RAM 2500 brings substantial towing and payload capability, and the available Cummins diesel was tweaked to deliver more power and better towing capacity. The model year also added a digital rearview mirror option and trailer reverse guidance, which make maneuvering a large truck easier. Owners also tend to praise its performance, safety features, and value for money, especially with the diesel engine.
At the same time, the 2021 RAM 2500 is not trying to hide its size or its truck-first priorities. The source notes that some shoppers wish for more modern interior features, including larger screens and cooled seats, so while it is well equipped, it may still leave some buyers wanting a bit more polish in the cabin.
Other model years to consider
- Average price: $61,990.00
- Good/great deal percentage: 49.2%
- User rating: 5 / 5
- Total listings: 587
- Average price: $37,700.00
- Good/great deal percentage: 26.2%
- User rating: 4.85 / 5
- Total listings: 344
- Average price: $47,401.00
- Good/great deal percentage: 54.0%
- User rating: 5 / 5
- Total listings: 315
This analysis is based on CarGurus' proprietary market data from August 11, 2026, CarGurus experts' opinions, and generative AI.
4.7 Overall rating
Filter by rating
Anonymous
Reviewed a 2021 RAM Power Wagon Crew Cab 4WD on May 30, 2026
Overal nice vehicle but it had small 17" wheels on it.
Anonymous
Reviewed a 2021 RAM 2500 on Jul 10, 2021
incredible. especially the artificial intelligence features. Updates such as bullet proof glass an added plus. great power and torque from the cummins. easily pushes other cars out of the way. very good to protect against attempted car jackers with the auto extracting prods We love this truck and applaud the RAM people for meeting consumer needs and wants in 2021. Great value. Very safe. Would buy again.
William S
Reviewed a 2021 RAM 2500 on Jan 28, 2022
It’s awesome. I’m glad my Ram 2500 single cab tradesmen 4x4 hemi is capable of doing everything I need. Kudos to Ram for still making a 3/4 ton 4x4 single cab without all the bells and whistles because people like me like basic things.
Anonymous
Reviewed a 2021 RAM 2500 on Mar 14, 2021
It basically drives itself. Fantastic vehicle and very fuel efficient for a huge diesel.
2021 RAM 2500 Trims
| Trim type | MSRP |
|---|---|
| Big Horn Crew Cab LB 4WD | $46,730 |
| Limited Mega Cab 4WD | $67,540 |
| Laramie Mega Cab 4WD | $55,240 |
| Tradesman Crew Cab LB 4WD | $42,080 |
| Power Wagon Crew Cab 4WD | $54,740 |
| Tradesman Crew Cab 4WD | $41,880 |
| Laramie Crew Cab 4WD | $53,740 |
| Big Horn Crew Cab 4WD | $46,530 |
2021 RAM 2500 Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 RAM 2500 prices has changed over time.
See more price trendsHow much does the 2021 RAM 2500 cost?
| Metric | Value |
|---|---|
| Current Average Price | $41,273 |
| Year-Round Low | $41,292.72 |
| Year-Round High | $44,839.92 |
| Average Price a Year Ago | $44,835 |
| Change vs. Last Year | −7.94% |
Prices have softened 7.94% compared to this time last year, making it a favorable time to shop this model year.
There are 3,388 listings available, which gives you a meaningful amount of inventory to compare.
If you find a listing below $41,292.72, that's toward the low end of the year-round range and worth acting on quickly.
Is the 2021 RAM 2500 a good car?
Yes — the 4.69/5 user rating points to strong owner satisfaction. Owners consistently praise its performance, safety features, and value for money, and many highlight the power and fuel efficiency, especially with the diesel engine. The spacious cabin also fits the truck’s appeal if you want a heavy-duty pickup that can handle both work and family use. With 30.4% of listings marked as good or great deals, you still have room to shop selectively.
Is the 2021 RAM 2500 reliable?
Owners rate it 4.69/5, a strong signal of long-term satisfaction.
The user feedback also points to a truck that feels dependable, with owners repeatedly calling out its performance and durability. That matters if you want a heavy-duty pickup you can count on for towing, hauling, and regular use over time. For used buyers, the main long-term ownership risk is ending up with a truck that has been worked hard without proper maintenance records.
What should I look for when buying a used 2021 RAM 2500?
Accident-free inventory is solid at 78.3% — always verify the vehicle history report.
You should start with a history report so you can confirm accident status, title history, and any major red flags before you get too far into the process. After that, prioritize a thorough inspection of the truck’s condition, especially signs of heavy use, because a heavy-duty pickup can vary a lot depending on how it was driven and maintained. Focus on overall wear, service history, and whether the truck still feels consistent with the kind of work you expect it to do.
Is now a good time to buy a used 2021 RAM 2500?
This looks like a moderate market, so you can be selective without expecting a deep bargain on every listing.
- Deal availability: 30.4% of listings are priced as good or great deals.
- Inventory: There are 3,388 listings available.
- Price trend: Prices have softened 7.94% compared with last year.
- Clean inventory: 78.3% of listings are accident-free.
If you find a listing below $41,292.72, that's toward the low end of the year-round range and worth acting on quickly.
What is the 2021 RAM 2500's resale value?
The current average of $41,273 sits slightly below last year's $44,835.
That price movement suggests the market has cooled, which can help you buy more carefully now but may also limit short-term upside if you plan to resell soon. If you buy at a strong price and keep the truck in clean condition, you give yourself a better chance of protecting value later. Strong owner satisfaction can also help support demand when it’s time to sell.
Vehicles with strong owner satisfaction ratings, like this model year's 4.69/5, tend to retain buyer demand, which supports resale value over time.
Should I buy a 2021 RAM 2500 or consider a different year?
If you're weighing the 2021 against nearby model years, here's how to think about it:
Choose the 2021 if:
- 30.4% of listings are priced as good or great deals.
- Accident-free inventory is solid at 78.3% — always verify the vehicle history report.
- Price trend: Prices have softened 7.94% compared with last year.
- Owners rate it 4.69/5 — a strong satisfaction signal.
Consider the 2020 if:
- At $39,910, the 2020 costs less than the current year's $41,273 average.
- It emphasizes luxury, capability, and advanced technology.
The bottom line: If you want the stronger current-market balance of price, inventory, and owner satisfaction, the 2021 is the better starting point. If your priority is spending less upfront, the 2020 is the more price-sensitive path and still offers a compelling heavy-duty truck experience.
These recommendations are based on CarGurus' proprietary market data from August 7, 2026, CarGurus experts' opinions, and generative AI.
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