Used 2021 Lexus RX 350 F Sport Handling AWD for SaleNationwide
32 vehicles found
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 89,607
- Stock #:
- T9193A
- VIN:
- 2T2YZMDA4MC279723
2021 Lexus RX
350 F Sport Handling AWD
89,607 mi
Hutchinson, KS
Good Deal
$35,018
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 77,063
- Stock #:
- T9542A
- VIN:
- 2T2YZMDA7MC288674
2021 Lexus RX
350 F Sport Handling AWD
77,063 mi
Pharr, TX
Good Deal
$34,720
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 57,001
- Stock #:
- W289394A
- VIN:
- 2T2YZMDA0MC274583
2021 Lexus RX
350 F Sport Handling AWD
57,001 mi
Jacksonville, FL
Fair Deal
$39,535
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 71,026
- Stock #:
- 70244398
- VIN:
- 2T2YZMDA5MC297521
2021 Lexus RX
350 F Sport Handling AWD
71,026 mi
Warner Robins, GA
Fair Deal
$36,998
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Transmission:
- 8-Speed Automatic
- Mileage:
- 73,537
- Stock #:
- 296528
- VIN:
- 2T2YZMDA3MC296528
2021 Lexus RX
350 F Sport Handling AWD
73,537 mi
Smyrna, TN
Fair Deal
$36,894
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 71,345
- Stock #:
- I143325O
- VIN:
- 2T2YZMDA1MC278447
Price drop
-$2,885
2021 Lexus RX
350 F Sport Handling AWD
71,345 mi
Lake City, FL
Good Deal
$36,390
$35,590
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 48,888
- Stock #:
- 401046
- VIN:
- 2T2YZMDAXMC306696
2021 Lexus RX
350 F Sport Handling AWD
48,888 mi
Murray, UT
Good Deal
$38,849
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 51,619
- Stock #:
- MC295923
- VIN:
- 2T2YZMDA4MC295923
2021 Lexus RX
350 F Sport Handling AWD
51,619 mi
Tampa, FL
Good Deal
$38,994
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 35,764
- Stock #:
- UC306564
- VIN:
- 2T2YZMDA4MC306564
2021 Lexus RX
350 F Sport Handling AWD
35,764 mi
San Antonio, TX
Good Deal
$43,802
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 60,767
- Stock #:
- P79153
- VIN:
- 2T2YZMDA4MC271086
Price drop
-$2,011
2021 Lexus RX
350 F Sport Handling AWD
60,767 mi
Montclair, CA
Good Deal
$37,334
$35,323
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 79,633
- Stock #:
- PM2836
- VIN:
- 2T2YZMDA1MC284765
2021 Lexus RX
350 F Sport Handling AWD
79,633 mi
Merrillville, IN
Fair Deal
$35,235
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- Automatic
- Mileage:
- 84,610
- Stock #:
- b261954
- VIN:
- 2T2SZMDA2MC261954
2021 Lexus RX
350 F Sport Handling AWD
84,610 mi
Hartford, CT
Fair Deal
$32,999
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Obsidian)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 78,160
- Stock #:
- M6958A
- VIN:
- 2T2YZMDA8MC269809
2021 Lexus RX
350 F Sport Handling AWD
78,160 mi
Montgomery, AL
Fair Deal
$37,038
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- Automatic
- Mileage:
- 65,950
- Stock #:
- MC280936
- VIN:
- 2T2YZMDA4MC280936
New arrival
2021 Lexus RX
350 F Sport Handling AWD
65,950 mi
Cerritos, CA
Fair Deal
$38,713
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 45,730
- Stock #:
- MC307878
- VIN:
- 2T2YZMDAXMC307878
New arrival
2021 Lexus RX
350 F Sport Handling AWD
45,730 mi
Gilroy, CA
Good Deal
$39,585
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 56,880
- Stock #:
- MC300316
- VIN:
- 2T2YZMDAXMC300316
New arrival
2021 Lexus RX
350 F Sport Handling AWD
56,880 mi
Houston, TX
Fair Deal
$39,206
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 78,661
- Stock #:
- H26918A
- VIN:
- 2T2YZMDA5MC272053
2021 Lexus RX
350 F Sport Handling AWD
78,661 mi
Wichita, KS
Fair Deal
$38,532
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Obsidian)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 49,939
- Stock #:
- MC260028A
- VIN:
- 2T2YZMDA1MC260028
2021 Lexus RX
350 F Sport Handling AWD
49,939 mi
Kennesaw, GA
Good Deal
$39,098
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Blue
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 58,922
- Stock #:
- 3017
- VIN:
- 2T2YZMDAXMC280407
New arrival
2021 Lexus RX
350 F Sport Handling AWD
58,922 mi
Auburn, WA
Fair Deal
$38,770
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Obsidian)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red w/Scored Aluminum Trim
- Transmission:
- Automatic
- Mileage:
- 46,758
- Stock #:
- TM502339A
- VIN:
- 2T2YZMDA8MC286481
Price drop
-$2,000
2021 Lexus RX
350 F Sport Handling AWD
46,758 mi
Macon, GA
Great Deal
$41,799
$39,799
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 74,519
- Stock #:
- 70170068
- VIN:
- 2T2YZMDA4MC273212
2021 Lexus RX
350 F Sport Handling AWD
74,519 mi
Bogart, GA
Fair Deal
$36,998
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Blue
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 44,953
- Stock #:
- 28506066
- VIN:
- 2T2YZMDA9MC276218
New arrival
2021 Lexus RX
350 F Sport Handling AWD
44,953 mi
Gastonia, NC
Fair Deal
$41,998
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Matador Red Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 48,637
- Stock #:
- MC297654
- VIN:
- 2T2YZMDA2MC297654
New arrival
2021 Lexus RX
350 F Sport Handling AWD
48,637 mi
Lewisville, TX
Fair Deal
$40,950
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Obsidian)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 46,155
- Stock #:
- 17UY0185
- VIN:
- 2T2YZMDA2MC305557
Price drop
-$1,391
2021 Lexus RX
350 F Sport Handling AWD
46,155 mi
Ogden, UT
No Rating
$41,200
$39,809
FAQs
How much does the Lexus RX 350 F Sport Handling AWD cost?
The average Lexus RX 350 F Sport Handling AWD costs about $35,361.64. The average price has decreased by -1.4% since last year. The 423 for sale on CarGurus range from $27,410 to $64,983 in price.
How many Lexus RX 350 F Sport Handling AWD vehicles have no reported accidents or damage?
351 out of 423 for sale have no reported accidents or damage.
What is the fuel economy of the Lexus RX 350 F Sport Handling AWD?
Depending on the engine and options, the Lexus RX 350 F Sport Handling AWD gets between 22 and 24 MPG/MPGe.
What fuel types are available?
Gasoline engines are available.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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