Used 2021 Lexus IS 350 F Sport RWD for SaleNationwide
109 vehicles found
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 61,239
- Stock #:
- L023412B
- VIN:
- JTHGZ1B29M5037581
2021 Lexus IS
350 F Sport RWD
61,239 mi
Gainesville, FL
Great Deal
$36,061
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White w/Black
- Transmission:
- Automatic
- Mileage:
- 46,361
- Stock #:
- M5038847
- VIN:
- JTHGZ1B24M5038847
2021 Lexus IS
350 F Sport RWD
46,361 mi
Orlando, FL
Good Deal
$36,492
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 52,054
- Stock #:
- 13999B
- VIN:
- JTHGZ1B26M5048425
2021 Lexus IS
350 F Sport RWD
52,054 mi
Martin, TN
Good Deal
$37,548
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Flare Red w/Black
- Transmission:
- Automatic
- Mileage:
- 20,330
- Stock #:
- M5040027
- VIN:
- JTHGZ1B29M5040027
2021 Lexus IS
350 F Sport RWD
20,330 mi
Tampa, FL
Great Deal
$40,595
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Black
- Transmission:
- Automatic
- Mileage:
- 62,039
- Stock #:
- P1418
- VIN:
- JTHGZ1B27M5041418
2021 Lexus IS
350 F Sport RWD
62,039 mi
San Jose, CA
Good Deal
$36,845
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 76,559
- Stock #:
- O695507O
- VIN:
- JTHGZ1B26M5041913
New arrival
2021 Lexus IS
350 F Sport RWD
76,559 mi
Holiday, FL
Great Deal
$33,790
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Black
- Transmission:
- Automatic
- Mileage:
- 91,409
- Stock #:
- M5038280
- VIN:
- JTHGZ1B20M5038280
2021 Lexus IS
350 F Sport RWD
91,409 mi
Avondale, AZ
Fair Deal
$34,394
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White w/Black Leather
- Transmission:
- Automatic
- Mileage:
- 16,460
- Stock #:
- P19238
- VIN:
- JTHGZ1B21M5039549
2021 Lexus IS
350 F Sport RWD
16,460 mi
Saint Louis, MO
Good Deal
$41,900
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Ginsumi
- Transmission:
- Automatic
- Mileage:
- 90,767
- Stock #:
- RKBB1140
- VIN:
- JTHGZ1B20M5043351
Price drop
-$1,376
2021 Lexus IS
350 F Sport RWD
90,767 mi
Buford, GA
Good Deal
$34,820
$33,444
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Grecian Water
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 70,709
- Stock #:
- M5045164
- VIN:
- JTHGZ1B20M5045164
New arrival
2021 Lexus IS
350 F Sport RWD
70,709 mi
Friendswood, TX
Fair Deal
$36,220
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 83,968
- Stock #:
- M5045492
- VIN:
- JTHGZ1B26M5045492
2021 Lexus IS
350 F Sport RWD
83,968 mi
Austin, TX
Good Deal
$34,709
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Infrared
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 25,589
- Stock #:
- G4542P
- VIN:
- JTHGZ1B21M5044265
2021 Lexus IS
350 F Sport RWD
25,589 mi
Duluth, GA
Great Deal
$40,018
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Flare Red W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 67,114
- Stock #:
- 000P5593
- VIN:
- JTHGZ1B28M5044747
2021 Lexus IS
350 F Sport RWD
67,114 mi
Placentia, CA
Fair Deal
$37,574
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 71,699
- Stock #:
- BM5042364
- VIN:
- JTHGZ1B24M5042364
2021 Lexus IS
350 F Sport RWD
71,699 mi
Plano, TX
Fair Deal
$36,175
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Grecian Water
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 38,559
- Stock #:
- 103153B
- VIN:
- JTHGZ1B28M5044439
2021 Lexus IS
350 F Sport RWD
38,559 mi
Jacksonville, FL
Fair Deal
$40,660
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Transmission:
- 8-Speed Automatic
- Mileage:
- 83,734
- Stock #:
- C8006
- VIN:
- JTHGZ1B28M5039533
New arrival
2021 Lexus IS
350 F Sport RWD
83,734 mi
Sanger, CA
Fair Deal
$35,073
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 67,587
- Stock #:
- A913108A
- VIN:
- JTHGZ1B26M5042706
New arrival
2021 Lexus IS
350 F Sport RWD
67,587 mi
Hollywood, FL
Great Deal
$33,815
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 76,190
- Stock #:
- P043453
- VIN:
- JTHGZ1B28M5043453
2021 Lexus IS
350 F Sport RWD
76,190 mi
Beaverton, OR
Fair Deal
$37,127
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Iridium
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Flare Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 37,307
- Stock #:
- PC16174
- VIN:
- JTHGZ1B23M5039469
2021 Lexus IS
350 F Sport RWD
37,307 mi
Countryside, IL
Fair Deal
$39,853
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Grecian Water
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Black
- Transmission:
- Automatic
- Mileage:
- 48,163
- Stock #:
- XZTB630B
- VIN:
- JTHGZ1B21M5045531
New arrival
2021 Lexus IS
350 F Sport RWD
48,163 mi
Charlotte, NC
Good Deal
$39,790
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 25,375
- Stock #:
- 29074515
- VIN:
- JTHGZ1B28M5038396
2021 Lexus IS
350 F Sport RWD
25,375 mi
Houston, TX
Good Deal
$39,998
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultrasonic Blue Mica 2.0
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 45,046
- Stock #:
- TN486469B
- VIN:
- JTHGZ1B25M5043961
New arrival
2021 Lexus IS
350 F Sport RWD
45,046 mi
Clermont, FL
Fair Deal
$38,701
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 51,203
- Stock #:
- 041114
- VIN:
- JTHGZ1B29M5041114
New arrival
2021 Lexus IS
350 F Sport RWD
51,203 mi
Albuquerque, NM
Fair Deal
$38,998
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultrasonic Blue Mica 2.0
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 90,068
- Stock #:
- 26523-1
- VIN:
- JTHGZ1B23M5048320
2021 Lexus IS
350 F Sport RWD
90,068 mi
Turlock, CA
Good Deal
$34,122
FAQs
How much does the Lexus IS 350 F Sport RWD cost?
The average Lexus IS 350 F Sport RWD costs about $35,353.58. The average price has increased by 5% since last year. The 355 for sale on CarGurus range from $25,999 to $68,125 in price.
How many Lexus IS 350 F Sport RWD vehicles have no reported accidents or damage?
294 out of 355 for sale have no reported accidents or damage.
What is the fuel economy of the Lexus IS 350 F Sport RWD?
Depending on the engine and options, the Lexus IS 350 F Sport RWD gets between 22 and 23 MPG (or EV battery range).
What fuel types are available?
Gasoline engines are available.
Relevant articles
The CarGurus Editorial Team
The Most Reliable Luxury Cars of 2026
Luxury cars give you the best of most things but which are the most reliable luxury cars you can buy? Our guide has all the details.
CarGurus Editorial Team
Best Lexus Deals in August 2026
Leasing a Lexus can be a great way to get into a new car from one of the most popular luxury brands at a more affordable monthly rate. Here are the best deals we've found this month on Lexus vehicles.
Cherise Threewitt
2026 Lexus IS Pricing, Specs, and Release Date
The Lexus IS gets a refresh for 2026 with new styling touches, a bigger infotainment display and instrument cluster, and retuned driving dynamics.
All Used CarsManual Transmission CarsLuxury CarsCars with Red InteriorCheap Manual CarsHybrid CarsSports CarsElectric SUVsCheap TrucksSmall CarsThird Row SUVsThree Quarter Ton TrucksLifted TrucksManual Transmission TrucksDiesel TrucksHybrid SUVsDually TrucksOne Ton TrucksCheap SUVsLifted Ford Trucks4x4 TrucksWork TrucksAWD SUVsFord TrucksChevrolet TrucksToyota TrucksTrucks Under $10,000Cars Under $15,000Sports Cars Under $20,000Trucks Under $20,000Used Sedans for Sale with Low MileageUsed SUVs / Crossovers for Sale with Low MileageUsed Hatchbacks for Sale with Low MileageUsed Convertibles for Sale with Low MileageUsed Vans for Sale with Low MileageUsed Minivans for Sale with Low MileageUsed Pickup Trucks for Sale with Low MileageUsed Coupes for Sale with Low MileageUsed Wagons for Sale with Low Mileage
