Used 2021 Lexus IS 350 F Sport RWD for SaleNationwide
112 vehicles found
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 61,239
- Stock #:
- L023412B
- VIN:
- JTHGZ1B29M5037581
2021 Lexus IS
350 F Sport RWD
61,239 mi
Gainesville, FL
Good Deal
$37,266
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Black
- Transmission:
- Automatic
- Mileage:
- 62,039
- Stock #:
- P1418
- VIN:
- JTHGZ1B27M5041418
2021 Lexus IS
350 F Sport RWD
62,039 mi
San Jose, CA
Good Deal
$36,845
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Blue Mica
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black W/Black
- Transmission:
- Automatic
- Mileage:
- 29,095
- Stock #:
- 27G0001A
- VIN:
- JTHGZ1B25M5042955
New arrival
2021 Lexus IS
350 F Sport RWD
29,095 mi
Lakeland, FL
Good Deal
$40,429
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White w/Black
- Transmission:
- Automatic
- Mileage:
- 46,361
- Stock #:
- M5038847
- VIN:
- JTHGZ1B24M5038847
2021 Lexus IS
350 F Sport RWD
46,361 mi
Orlando, FL
Good Deal
$36,952
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 86,925
- Stock #:
- B979
- VIN:
- JTHGZ1B28M5037927
New arrival
2021 Lexus IS
350 F Sport RWD
86,925 mi
Owasso, OK
Fair Deal
$35,698
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultrasonic Blue Mica 2.0
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 45,046
- Stock #:
- TN486469B
- VIN:
- JTHGZ1B25M5043961
New arrival
2021 Lexus IS
350 F Sport RWD
45,046 mi
Clermont, FL
Fair Deal
$38,711
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 74,479
- Stock #:
- XBP8642
- VIN:
- JTHGZ1B25M5044219
2021 Lexus IS
350 F Sport RWD
74,479 mi
Libertyville, IL
Fair Deal
$37,407
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- Automatic
- Mileage:
- 16,460
- Stock #:
- P19238
- VIN:
- JTHGZ1B21M5039549
2021 Lexus IS
350 F Sport RWD
16,460 mi
Saint Louis, MO
Good Deal
$41,900
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Flare Red W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 47,359
- Stock #:
- D1575
- VIN:
- JTHGZ1B24M5038167
2021 Lexus IS
350 F Sport RWD
47,359 mi
Summerville, SC
Great Deal
$37,969
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Flare Red w/Black
- Transmission:
- Automatic
- Mileage:
- 20,330
- Stock #:
- M5040027
- VIN:
- JTHGZ1B29M5040027
2021 Lexus IS
350 F Sport RWD
20,330 mi
Tampa, FL
Good Deal
$40,595
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultrasonic Blue Mica 2.0
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 42,089
- Stock #:
- T04269LC
- VIN:
- JTHGZ1B24M5039318
New arrival
2021 Lexus IS
350 F Sport RWD
42,089 mi
Temecula, CA
Fair Deal
$40,528
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 62,059
- Stock #:
- TM5044655
- VIN:
- JTHGZ1B23M5044655
Price drop
-$2,189
2021 Lexus IS
350 F Sport RWD
62,059 mi
Birmingham, AL
Great Deal
$35,186
$33,686
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultrasonic Blue Mica 2.0
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 90,068
- Stock #:
- 26523-1
- VIN:
- JTHGZ1B23M5048320
2021 Lexus IS
350 F Sport RWD
90,068 mi
Turlock, CA
Good Deal
$34,122
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 26,555
- Stock #:
- M5038203P
- VIN:
- JTHGZ1B24M5038203
2021 Lexus IS
350 F Sport RWD
26,555 mi
Richardson, TX
Good Deal
$41,212
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Black
- Transmission:
- Automatic
- Mileage:
- 91,409
- Stock #:
- M5038280
- VIN:
- JTHGZ1B20M5038280
2021 Lexus IS
350 F Sport RWD
91,409 mi
Avondale, AZ
Fair Deal
$34,832
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 52,054
- Stock #:
- 13999B
- VIN:
- JTHGZ1B26M5048425
2021 Lexus IS
350 F Sport RWD
52,054 mi
Martin, TN
Good Deal
$37,548
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Flare Red W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 67,114
- Stock #:
- 000P5593
- VIN:
- JTHGZ1B28M5044747
2021 Lexus IS
350 F Sport RWD
67,114 mi
Placentia, CA
Fair Deal
$37,574
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 96,138
- Stock #:
- F041084
- VIN:
- JTHGZ1B24M5041084
2021 Lexus IS
350 F Sport RWD
96,138 mi
Fishers, IN
Good Deal
$32,851
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 83,968
- Stock #:
- M5045492
- VIN:
- JTHGZ1B26M5045492
2021 Lexus IS
350 F Sport RWD
83,968 mi
Austin, TX
Good Deal
$35,400
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Flare Red w/Black
- Transmission:
- Automatic
- Mileage:
- 85,981
- Stock #:
- M5042732
- VIN:
- JTHGZ1B27M5042732
2021 Lexus IS
350 F Sport RWD
85,981 mi
Houston, TX
Fair Deal
$34,724
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 55,637
- Stock #:
- M5046197
- VIN:
- JTHGZ1B29M5046197
New arrival
2021 Lexus IS
350 F Sport RWD
55,637 mi
Granbury, TX
Fair Deal
$39,083
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Cloudburst Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black w/Black
- Transmission:
- Automatic
- Mileage:
- 44,345
- Stock #:
- 038020
- VIN:
- JTHGZ1B27M5038020
2021 Lexus IS
350 F Sport RWD
44,345 mi
Rancho Cordova, CA
Good Deal
$38,668
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 48,398
- Stock #:
- TI043249
- VIN:
- JTHGZ1B29M5043249
Price drop
-$936
2021 Lexus IS
350 F Sport RWD
48,398 mi
Plantation, FL
Good Deal
$37,475
$36,539
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Iridium
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Flare Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 37,269
- Stock #:
- PC16174
- VIN:
- JTHGZ1B23M5039469
2021 Lexus IS
350 F Sport RWD
37,269 mi
Countryside, IL
Good Deal
$39,853
FAQs
How much does the Lexus IS 350 F Sport RWD cost?
The average Lexus IS 350 F Sport RWD costs about $35,367.45. The average price has increased by 5.6% since last year. The 357 for sale on CarGurus range from $25,680 to $59,332 in price.
How many Lexus IS 350 F Sport RWD vehicles have no reported accidents or damage?
296 out of 357 for sale have no reported accidents or damage.
What is the fuel economy of the Lexus IS 350 F Sport RWD?
Depending on the engine and options, the Lexus IS 350 F Sport RWD gets between 22 and 23 MPG (or EV battery range).
What fuel types are available?
Gasoline engines are available.
Relevant articles
The CarGurus Editorial Team
The Most Reliable Luxury Cars of 2026
Luxury cars give you the best of most things but which are the most reliable luxury cars you can buy? Our guide has all the details.
CarGurus Editorial Team
Best Lexus Deals in August 2026
Leasing a Lexus can be a great way to get into a new car from one of the most popular luxury brands at a more affordable monthly rate. Here are the best deals we've found this month on Lexus vehicles.
Cherise Threewitt
2026 Lexus IS Pricing, Specs, and Release Date
The Lexus IS gets a refresh for 2026 with new styling touches, a bigger infotainment display and instrument cluster, and retuned driving dynamics.
All Used CarsManual Transmission CarsLuxury CarsCars with Red InteriorCheap Manual CarsHybrid CarsSports CarsElectric SUVsCheap TrucksSmall CarsThird Row SUVsThree Quarter Ton TrucksLifted TrucksManual Transmission TrucksDiesel TrucksHybrid SUVsDually TrucksOne Ton TrucksCheap SUVsLifted Ford Trucks4x4 TrucksWork TrucksAWD SUVsFord TrucksChevrolet TrucksToyota TrucksTrucks Under $10,000Cars Under $15,000Sports Cars Under $20,000Trucks Under $20,000Used Sedans for Sale with Low MileageUsed SUVs / Crossovers for Sale with Low MileageUsed Hatchbacks for Sale with Low MileageUsed Convertibles for Sale with Low MileageUsed Vans for Sale with Low MileageUsed Minivans for Sale with Low MileageUsed Pickup Trucks for Sale with Low MileageUsed Coupes for Sale with Low MileageUsed Wagons for Sale with Low Mileage
