Used 2021 Lexus IS 300 AWD for SaleNationwide
15 vehicles found
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- 6-Speed Automatic
- Mileage:
- 47,341
- Stock #:
- U1500469A
- VIN:
- JTHC81F22M5043329
New arrival
2021 Lexus IS
300 AWD
47,341 mi
North Attleboro, MA
Good Deal
$33,522
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Matador Red Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Caramel
- Transmission:
- 6-Speed Automatic
- Mileage:
- 43,513
- Stock #:
- SM0484-5
- VIN:
- JTHC81F29M5044039
2021 Lexus IS
300 AWD
43,513 mi
Manchester, MO
Great Deal
$31,913
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Cloudburst Gray[xccloudburst]
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Caramel Nuluxe® With Black Metallic Trim
- Transmission:
- Automatic
- Mileage:
- 63,751
- Stock #:
- G26385B
- VIN:
- JTHC81F21M5046562
![Cloudburst Gray[xccloudburst] 2021 Lexus IS Sedan All-Wheel Drive Automatic](https://static.cargurus.com/images/forsale/2026/09/18/13/19/2021_lexus_is-pic-2424273498442068254-1024x768.jpeg?io=true&width=640&height=480&fit=bounds&format=jpg&auto=webp)
2021 Lexus IS
300 AWD
63,751 mi
Gladstone, OR
Good Deal
$33,150
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Flare Red
- Transmission:
- 6-Speed Automatic
- Mileage:
- 65,296
- Stock #:
- 7045380
- VIN:
- JTHG81F2XM5045380
New arrival
2021 Lexus IS
300 AWD
65,296 mi
Moorhead, MN
Good Deal
$31,847
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 33,654
- Stock #:
- IQU1202R
- VIN:
- JTHC81F23M5044926
2021 Lexus IS
300 AWD
33,654 mi
Bayside, NY
Good Deal
$34,570
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 37,585
- Stock #:
- 262720
- VIN:
- JTHD81F27M5046666
2021 Lexus IS
300 AWD
37,585 mi
Kennewick, WA
Good Deal
$34,500
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Black
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 24,845
- Stock #:
- 8802
- VIN:
- JTHD81F23M5045580
2021 Lexus IS
300 AWD
24,845 mi
Yakima, WA
Fair Deal
$38,700
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Matador Red Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Flare Red
- Transmission:
- 6-Speed Automatic
- Mileage:
- 30,693
- Stock #:
- RU047081
- VIN:
- JTHC81F21M5047081
2021 Lexus IS
300 AWD
30,693 mi
Wilmington, DE
Great Deal
$34,371
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Caramel
- Transmission:
- 6-Speed Automatic
- Mileage:
- 55,176
- Stock #:
- H61537A
- VIN:
- JTHC81F27M5046260
2021 Lexus IS
300 AWD
55,176 mi
Baltimore, MD
Fair Deal
$32,296
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Eminent White Pearl - 085
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black - 21
- Transmission:
- Automatic
- Mileage:
- 4,206
- Stock #:
- 226223
- VIN:
- JTHC81F27M5043925
2021 Lexus IS
300 AWD
4,206 mi
Media, PA
Good Deal
$39,377
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Matador Red Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Caramel
- Transmission:
- 6-Speed Automatic
- Mileage:
- 64,609
- Stock #:
- TG54905A
- VIN:
- JTHC81F23M5047017
New arrival
2021 Lexus IS
300 AWD
64,609 mi
Ramsey, NJ
Fair Deal
$32,299
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 28,279
- Stock #:
- M5044823
- VIN:
- JTHC81F24M5044823
2021 Lexus IS
300 AWD
28,279 mi
Voorhees, NJ
Fair Deal
$37,136
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- 6-Speed Automatic
- Mileage:
- 58,310
- Stock #:
- T14288
- VIN:
- JTHC81F23M5045915
New arrival
2021 Lexus IS
300 AWD
58,310 mi
Delaware, OH
No Rating
No Price Listed
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 79,073
- Stock #:
- 54L1417P
- VIN:
- JTHC81F25M5047391
New arrival
2021 Lexus IS
300 AWD
79,073 mi
Wichita, KS
No Rating
No Price Listed
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Grecian Water
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 30,388
- Stock #:
- 82F09103
- VIN:
- JTHC81F28M5044369
Photos coming soon
2021 Lexus IS
300 AWD
30,388 mi
Cleveland, OH
High Priced
$38,394
FAQs
How much does the Lexus IS 300 AWD cost?
The average Lexus IS 300 AWD costs about $34,622.36. The average price has increased by 1.4% since last year. The 263 for sale on CarGurus range from $10,345 to $44,899 in price.
How many Lexus IS 300 AWD vehicles have no reported accidents or damage?
131 out of 263 for sale have no reported accidents or damage.
What is the fuel economy of the Lexus IS 300 AWD?
Depending on the engine and options, the Lexus IS 300 AWD gets between 20 and 22 MPG/MPGe.
What fuel types are available?
Gasoline engines are available.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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