Used 2022 Lexus RX for Sale nearMemphis, TN
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Transmission:
- 8-Speed Automatic
- Mileage:
- 54,698
- Stock #:
- P6980
- VIN:
- 2T2HZMAA9NC258145

-$2,002

Sponsored by Mt Moriah Auto Sales
2022 Lexus RX
350 FWD
54,698 mi
$40,995
$38,993
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 44,230
- Stock #:
- C18091
- VIN:
- 2T2AZMAA1NC221737

Sponsored Listing
2022 Lexus RX
350 FWD
44,230 mi
$40,640
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 290 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 25,103
- Stock #:
- N2028110RB
- VIN:
- JTJJZKEA2N2028110

Sponsored Listing
2022 Lexus RX
350L Luxury FWD
25,103 mi
$49,125
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 67,669
- Stock #:
- MC208005
- VIN:
- 2T2HZMAA9MC208005

2021 Lexus RX
350 FWD
67,669 mi
$35,345
- Year:
- 2023
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 275 hp 2.4L I4
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Macadamia w/Ash Bamboo
- Transmission:
- 8-Speed Automatic
- Mileage:
- 48,581
- Stock #:
- PC004939A
- VIN:
- 2T2BAMBA6PC004939

2023 Lexus RX
350 Luxury FWD
48,581 mi
$46,425
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Nightfall Mica
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 56,716
- Stock #:
- 53063A
- VIN:
- 2T2AZMAA1NC237789

2022 Lexus RX
350 FWD
56,716 mi
$33,665
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 290 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 25,103
- Stock #:
- N2028110RB
- VIN:
- JTJJZKEA2N2028110

2022 Lexus RX
350L Luxury FWD
25,103 mi
$49,125
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 290 hp 3.5L V6
- Exterior color:
- Silver
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 85,508
- Stock #:
- 70225241
- VIN:
- JTJHZKFA5M2028663

2021 Lexus RX
350L AWD
85,508 mi
$35,147
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Transmission:
- 8-Speed Automatic
- Mileage:
- 112,447
- Stock #:
- V074388A
- VIN:
- 2T2HZMAA0MC218485

2021 Lexus RX
350 FWD
112,447 mi
$31,450
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 83,000
- Stock #:
- 4845
- VIN:
- 2T2YZMDA5NC319907

2022 Lexus RX
350 F Sport Handling AWD
83,000 mi
$33,743
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- Automatic
- Mileage:
- 113,518
- Stock #:
- 4716
- VIN:
- 2T2HZMAAXMC186676

2021 Lexus RX
350 FWD
113,518 mi
$29,226
- Year:
- 2023
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 275 hp 2.4L I4
- Exterior color:
- Gray
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 55,160
- Stock #:
- S067209B
- VIN:
- 2T2BAMCA6PC006513

2023 Lexus RX
350 F Sport Handling AWD
55,160 mi
$48,950
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 117,835
- Stock #:
- TMC214930
- VIN:
- 2T2HZMAA8MC214930

2021 Lexus RX
350 FWD
117,835 mi
$29,899
CarGurus Analysis:
2022 Lexus RX
With 149 currently listed for sale and an average price of $41,326, 63.8% of 2022 Lexus RX listings on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Lexus RX 4.77 / 5 stars and CarGurus experts gave it a 7.33 / 10.
100.0% of 2022 Lexus RX listings on CarGurus are accident free.
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Caramel
- Transmission:
- 8-Speed Automatic
- Mileage:
- 62,645
- Stock #:
- 182407
- VIN:
- 2T2HZMAA7MC182407

2021 Lexus RX
350 FWD
62,645 mi
$33,712
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 33,426
- Stock #:
- NC259651
- VIN:
- 2T2HZMAA7NC259651

2022 Lexus RX
350 FWD
33,426 mi
$41,076
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 290 hp 3.5L V6
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 110,094
- Stock #:
- 27AS583T
- VIN:
- JTJHZKFA6N2036157

2022 Lexus RX
350L AWD
110,094 mi
$32,470
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black Leather
- Transmission:
- Automatic
- Mileage:
- 40,575
- Stock #:
- P12304
- VIN:
- 2T2AZMDAXMC282384

2021 Lexus RX
350 AWD
40,575 mi
$37,287
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- Automatic
- Mileage:
- 62,481
- Stock #:
- 70130943
- VIN:
- 2T2HZMAA5NC236224

2022 Lexus RX
350 FWD
62,481 mi
$38,497
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 44,230
- Stock #:
- C18091
- VIN:
- 2T2AZMAA1NC221737

2022 Lexus RX
350 FWD
44,230 mi
$40,640
- Year:
- 2023
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 275 hp 2.4L I4
- Exterior color:
- White Pearl
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Macadamia
- Transmission:
- 8-Speed Automatic
- Mileage:
- 32,566
- Stock #:
- 7K3700P
- VIN:
- 2T2BAMBA8PC016512

2023 Lexus RX
350 FWD
32,566 mi
$41,915
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 38,644
- Stock #:
- D5844L
- VIN:
- 2T2YZMDA3NC363226

2022 Lexus RX
350 F Sport Handling AWD
38,644 mi
$45,696
- Year:
- 2023
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 275 hp 2.4L I4
- Exterior color:
- Iridium
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 22,977
- Stock #:
- A18966A
- VIN:
- 2T2BAMCA4PC014108

2023 Lexus RX
350 Luxury AWD
22,977 mi
$51,299
- Year:
- 2023
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 275 hp 2.4L I4
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Macadamia w/Ash Bamboo
- Transmission:
- 8-Speed Automatic
- Mileage:
- 48,581
- Stock #:
- PC004939A
- VIN:
- 2T2BAMBA6PC004939

Sponsored Listing
2023 Lexus RX
350 Luxury FWD
48,581 mi
$46,425
CarGurus Analysis: 2022 Lexus RX
overall
Summary
With 149 currently listed for sale and an average price of $41,326, 63.8% of 2022 Lexus RX listings on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Lexus RX 4.77 / 5 stars and CarGurus experts gave it a 7.33 / 10.
100.0% of 2022 Lexus RX listings on CarGurus are accident free.
Why it stands out
The 2022 Lexus RX stands out as a luxury SUV that leans more toward comfort and refinement than outright performance. It has an attractive design, luxury amenities, driving comfort, and a reputation for tried-and-true reliability, which helps explain why it remains a best-seller. For buyers who value a smooth, relaxed driving experience, that combination is a major part of its appeal.
For 2022, the RX is a carryover model with minimal changes, including new colors and a standalone fog lamps option. It also offers great ride quality and standard advanced safety features. At the same time, its potentially polarizing design and poor ergonomic design are worth noting, and the RX does not offer much in terms of performance. Owners also commonly praise its comfort, features, and luxury feel, while some mention a lack of pickup power and concerns about gas mileage.
Other model years to consider
- 2023 Lexus RX
- Average price: $47,604
- Good/great deal percentage: 66.9%
- User rating: 5 / 5
- Total listings: 169
- 2020 Lexus RX
- Average price: $33,346
- Good/great deal percentage: 74.6%
- User rating: 4.88 / 5
- Total listings: 118
- 2021 Lexus RX
- Average price: $31,314
- Good/great deal percentage: 73.7%
- User rating: 4.92 / 5
- Total listings: 114
Similar models to consider
- 2022 Toyota Venza
- Average price: $28,992
- Good/great deal percentage: 29.8%
- User rating: 4.71 / 5
- Total listings: 47
- 2022 Acura RDX
- Average price: $30,347
- Good/great deal percentage: 65.3%
- User rating: 4.6 / 5
- Total listings: 101
- 2022 BMW X3
- Average price: $25,876
- Good/great deal percentage: 85.1%
- User rating: 4.92 / 5
- Total listings: 342
This analysis is based on CarGurus' proprietary market data from October 12, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
4.8 Overall rating
Filter by rating
Marc G
Reviewed a 2022 Lexus RX on Dec 29, 2025
Good and reliable vehicle. Luxury is the cornerstone of this SUV.
Larry M
Reviewed a 2022 Lexus RX on Jul 24, 2026
I currently own a Lexus RX350. It’s been a reliable vehicle with a great quiet ride. I am looking at a newer RX350 at the current time
Terry C
Reviewed a 2022 Lexus RX on Apr 12, 2025
Non turbo Toyota reliability and smoothness and composure of a S class.
Uday T
Reviewed a 2022 Lexus RX on Jun 6, 2023
Great car, drives smooth. Lacks pick up power for a V6
2022 Lexus RX Trims
| Trim type | MSRP |
|---|---|
| 350L Luxury AWD | $56,150 |
| 350L Luxury FWD | $54,750 |
| 350 F Sport AWD | $50,800 |
| 350L FWD | $48,750 |
| 350L AWD | $50,150 |
| 350 F Sport Handling AWD | $53,200 |
| 350 AWD | $47,320 |
| 350 FWD | $45,920 |
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2022 Lexus RX Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Lexus RX prices has changed over time.
See more price trends2022 Lexus RX Pricing Analysis: Memphis, TN Market Report
Pricing in Nearby Cities
Market Area: Memphis, TN
Key Insights
- Highest-Price Market: Tupelo, MS leads with an average price of $41,919, indicating a premium market for the Lexus RX in this area.
- Best Value: Greenwood, MS offers the lowest average price at $38,960, suggesting a more budget-friendly option for shoppers.
- Inventory Drives Stability: Jackson, TN has the most listings at 178, which may contribute to more competitive pricing and availability.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Jackson, TN | 178 | $40,038 |
| Tupelo, MS | 173 | $41,919 |
| Greenwood, MS | 137 | $38,960 |
Pricing by Trim Packages
Key Insights
- Volume Leader: The 350 FWD trim has the highest inventory with 202 listings, making it the most accessible option for buyers.
- Premium Spread: The 350 F Sport Handling AWD trim is priced at $53,200, reflecting a significant premium over the base trims.
- Drivetrain Effect: All trims feature the same engine, but the AWD variants generally command higher prices, indicating a preference for all-wheel drive in this market.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| 350 FWD | 202 | $45,920 | FWD | 3.5L 295 hp V6 |
| 350 AWD | 127 | $47,320 | AWD | 3.5L 295 hp V6 |
| 350 F Sport Handling AWD | 37 | $53,200 | AWD | 3.5L 295 hp V6 |
| 350 F Sport AWD | 54 | $50,800 | AWD | 3.5L 295 hp V6 |
| 350L AWD | 19 | $50,150 | AWD | 3.5L 290 hp V6 |
| 350L FWD | 31 | $48,750 | FWD | 3.5L 290 hp V6 |
| 350 F Sport FWD | 16 | $49,400 | FWD | 3.5L 295 hp V6 |
Pricing Analysis by Model Year
Key Insights
- New-Car Premium: The 2025 model year shows a 14.3% increase over its starting MSRP, indicating strong demand for newer models.
- Depreciation Curve: The 2017 model has experienced the steepest depreciation at -43.2%, highlighting significant value loss over time.
- Best Value Sweet Spot: The 2022 model year is priced at an average of $42,082, which is -8.4% below its MSRP, making it a potentially attractive option for budget-conscious buyers.
Model Year Pricing
| Model Year | Starting MSRP | Avg Price | Avg Price vs Starting MSRP |
|---|---|---|---|
| 2025 | $48,975 | $55,998 | +14.3% |
| 2024 | $48,600 | $56,425 | +16.1% |
| 2023 | $47,800 | $46,139 | -3.5% |
| 2022 | $45,920 | $42,082 | -8.4% |
| 2021 | $45,220 | $31,314 | -30.8% |
| 2020 | $44,150 | $34,677 | -21.5% |
| 2019 | $43,820 | $27,293 | -37.7% |
| 2018 | $43,470 | $30,500 | -29.8% |
| 2017 | $43,220 | $24,546 | -43.2% |
| 2016 | $41,900 | $24,425 | -41.7% |
These recommendations are based on CarGurus' proprietary market data from October 7, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
How much does the 2022 Lexus RX cost?
| Metric | Value |
|---|---|
| Current Average Price | $38,752 |
| Year-Round Low | $38,752 |
| Year-Round High | $40,899 |
| Average Price a Year Ago | $40,904 |
| Change vs. Last Year | −5.26% |
Prices have softened 5.26% compared to this time last year, making it a favorable time to shop this model year.
There are 2,100 listings available, which suggests you have a solid amount of inventory to compare.
Is the 2022 Lexus RX a good car?
Yes — the 2022 Lexus RX earns a 4.77/5 user rating and a 7.33/10 expert rating. The model scores 8/10 across Cost effectiveness and Safety.
Owners consistently praise its comfort, smooth ride, luxury feel, and feature content, and they also highlight its advanced tech. The main trade-offs are its lack of pickup power and concerns about gas mileage. For you, that means the RX makes the most sense if you want a relaxed luxury SUV rather than a quick one, especially since the 2022 model is a carryover with only minor updates and is aimed at buyers who value refinement over performance. Good and great deals account for 38.2% of listings, which gives you some room to shop selectively.
Is the 2022 Lexus RX reliable?
Owners rate it 4.77/5, a strong signal of long-term satisfaction.
The owner feedback points to a vehicle that feels comfortable, dependable, and easy to live with over time. Expert commentary also emphasizes the RX’s reputation for comfort, quality, and reliability, which reinforces the idea that this is a model built for steady ownership rather than drama. The RX’s competitive pricing and strong value proposition further support that impression, and the available maintenance-friendly ownership experience helps keep day-to-day use straightforward. For used buyers, the main long-term risk is less about durability and more about whether the vehicle’s condition and maintenance history match its reputation.
What should I look for when buying a used 2022 Lexus RX?
Accident-free inventory is solid at 82% — always verify the vehicle history report.
You should still run a history report on any candidate, even if the listing looks clean at first glance. Prioritize a pre-purchase inspection, especially if you’re considering a higher-mileage example or one with optional equipment. Focus on overall condition, interior wear, and whether the vehicle’s features and trim level match the asking price.
Key things to evaluate:
- Trim level: The gas model is offered in base 350, F Sport, and L trims. The base and L versions emphasize comfort and luxury, while F Sport adds a more athletic look with 20-inch wheels, black-housing mirrors, dark window trim, F Sport badging, and a unique front fascia. The base and L trims use 18-inch wheels, so the feature gap is noticeable if you want a more upscale appearance.
- Powertrain: The RX 350 uses a 3.5-liter V6 with 295 horsepower and 267 pound-feet of torque, paired with an eight-speed automatic. Front-wheel drive is standard, with all-wheel drive available. The hybrid RX 450h adds two electric motors and produces 308 hp, but that is a separate hybrid model.
- Safety package: Lexus Safety System 2.0+ is standard and includes adaptive cruise control with stop-and-go, lane-departure warning with steering assist, road-sign recognition, lane-keeping assist, lane-tracing assist, pre-collision braking with cyclist and pedestrian detection, and intelligent high beams. Blind-spot monitoring, rear cross-traffic alert, a head-up display, and Lexus Enform Safety Connect are also standard. The Top Safety Pick result depends on the optional triple-beam LED headlights.
- Infotainment: Standard infotainment uses an 8-inch touchscreen, with a 12.3-inch screen available. Android Auto and Apple CarPlay are available, along with wireless charging, Amazon Alexa compatibility, a WiFi hotspot, navigation with cloud-based updates, and multiple premium audio options.
- Fuel efficiency: The RX 350 returns 20 mpg city, 27 mpg highway, and 23 combined. AWD or the three-row L model lowers those figures by 1 mpg, and the 350L AWD is rated at 18 mpg city, 25 mpg highway, and 23 combined. The RX 450h is rated at 30 mpg combined, with 31 mpg city and 28 mpg highway.
Which 2022 Lexus RX trim should I buy?
The 2022 Lexus RX is offered in 3 trim levels: base 350, F Sport, and L.
Here's the short version:
- base 350: This is the most straightforward choice if you want the RX’s core strengths — comfort, luxury feel, and strong value — without paying for the sportier appearance or the extra seating of the L model. It’s the best-value starting point for most shoppers.
- F Sport: Choose this if you want the most aggressive styling and a more athletic look, including the larger wheels, unique front fascia, and F Sport-specific interior touches. It suits you best if appearance matters more than actual performance gains.
- L: Pick this if you need the three-row, 7-passenger layout. It’s the right call when passenger flexibility matters more than the standard two-row setup.
The safety package is standard across the lineup, but the Top Safety Pick result depends on the optional triple-beam LED headlights.
Is now a good time to buy a used 2022 Lexus RX?
This is a moderate market for selective buyers, so you can shop carefully and still find worthwhile listings.
- Deal availability: 38.2% of listings are priced as good or great deals.
- Inventory: There are 2,100 listings available.
- Price trend: Prices have softened 5.26% compared with last year.
- Clean inventory: 82.0% of listings are accident-free.
If you find a listing below $38,752, that's toward the low end of the year-round range and worth acting on quickly.
What is the 2022 Lexus RX's resale value?
The current average of $38,752 sits slightly below last year's $40,904.
That price movement suggests the RX has softened enough to give you a better entry point now, but it also means future resale will depend heavily on how well you buy and maintain the vehicle. If you purchase near the low end of the range and keep the SUV in clean condition, you’re better positioned to limit depreciation. The RX’s broad appeal and strong reputation should help support demand, especially among shoppers who want a comfortable luxury SUV with a proven nameplate.
Vehicles with strong owner satisfaction ratings, like this model year's 4.77/5, tend to retain buyer demand, which supports resale value over time.
Is the 2022 Lexus RX safe?
The 2022 Lexus RX earns a Top Safety Pick from IIHS, but only when equipped with the optional triple-beam LED headlights, and it earns four-star ratings overall from NHTSA, with five-star side crash results and four-star frontal crash and rollover ratings.
It earns an 8/10 safety score from our experts.
Lexus Safety System 2.0+ is standard and includes adaptive cruise control with stop-and-go, lane-departure warning with steering assist, road-sign recognition, lane-keeping assist, lane-tracing assist, a pre-collision system with cyclist and pedestrian detection, and intelligent high beams. Standard equipment also includes blind-spot monitoring, rear cross-traffic alert, a head-up display, and Lexus Enform Safety Connect. The main caveat is that the RX misses the IIHS top-tier plus designation because of its headlights rating, so you should pay close attention to headlight equipment when shopping.
Should I buy a 2022 Lexus RX or consider a different year?
If you're weighing the 2022 against nearby model years, here's how to think about it:
Choose the 2022 if:
- 38.2% of listings are priced as good or great deals.
- Accident-free inventory is solid at 82% — always verify the vehicle history report.
- Price trend: Prices have softened 5.26% compared with last year.
- Owners rate it 4.77/5 — a strong satisfaction signal.
- The 2022 is a carryover model with minimal changes, including new colors and a standalone fog lamps option.
Consider the 2021 if:
- At $35,354, the 2021 costs less than the current year's $38,752 average.
- It adds a few tech upgrades and new standard safety systems.
Consider the 2023 if:
- At $45,654, the 2023 costs more than the current year's $38,752 average.
- The redesign adds more dynamic and technological polish.
The bottom line: The 2022 is the right pick if you want the familiar RX formula at a softer price than newer redesigns. If you’re especially price-sensitive, the 2021 is the value play; if you want the latest redesign and can spend more, the 2023 is the upgrade path.
These recommendations are based on CarGurus' proprietary market data from October 6, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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