Used 2022 Lexus RX 350 F SPORT Handling AWD for SaleNationwide
75 vehicles found
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 69,743
- Stock #:
- T1103A
- VIN:
- 2T2YZMDA3NC320859
New arrival
2022 Lexus RX
350 F SPORT Handling AWD
69,743 mi
San Antonio, TX
Good Deal
$38,912
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 38,257
- Stock #:
- 266677A
- VIN:
- 2T2YZMDA1NC346666
2022 Lexus RX
350 F SPORT Handling AWD
38,257 mi
Baton Rouge, LA
Good Deal
$44,020
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 16,458
- Stock #:
- NC356746
- VIN:
- 2T2YZMDA5NC356746
2022 Lexus RX
350 F SPORT Handling AWD
16,458 mi
Lynnwood, WA
Fair Deal
$50,364
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 31,855
- Stock #:
- SB4270
- VIN:
- 2T2YZMDA6NC320886
2022 Lexus RX
350 F SPORT Handling AWD
31,855 mi
Quakertown, PA
Fair Deal
$44,806
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 97,152
- Stock #:
- C324092
- VIN:
- 2T2YZMDA0NC324092
2022 Lexus RX
350 F SPORT Handling AWD
97,152 mi
Tampa, FL
Fair Deal
$33,428
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 107,042
- Stock #:
- U314749
- VIN:
- 2T2YZMDAXNC314749
2022 Lexus RX
350 F SPORT Handling AWD
107,042 mi
Oakland Park, FL
Good Deal
$30,605
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 100,183
- Stock #:
- BC00021A
- VIN:
- 2T2YZMDA6NC334061
2022 Lexus RX
350 F SPORT Handling AWD
100,183 mi
Tucson, AZ
Fair Deal
$32,899
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 59,071
- Stock #:
- C342532
- VIN:
- 2T2YZMDA4NC342532
2022 Lexus RX
350 F SPORT Handling AWD
59,071 mi
Orlando, FL
Good Deal
$39,249
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- Automatic
- Mileage:
- 41,209
- Stock #:
- T01259A
- VIN:
- 2T2YZMDA6NC355606
New arrival
2022 Lexus RX
350 F SPORT Handling AWD
41,209 mi
Charleston, SC
Fair Deal
$45,798
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 69,812
- Stock #:
- NC312067
- VIN:
- 2T2YZMDA7NC312067
2022 Lexus RX
350 F SPORT Handling AWD
69,812 mi
Henderson, TX
Great Deal
$35,152
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 35,343
- Stock #:
- 355068
- VIN:
- 2T2YZMDA4NC355068
2022 Lexus RX
350 F SPORT Handling AWD
35,343 mi
Duluth, GA
Good Deal
$44,690
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 23,809
- Stock #:
- NC340707
- VIN:
- 2T2YZMDA3NC340707
2022 Lexus RX
350 F SPORT Handling AWD
23,809 mi
Mt Laurel, NJ
Fair Deal
$45,989
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 38,644
- Stock #:
- D5844L
- VIN:
- 2T2YZMDA3NC363226
2022 Lexus RX
350 F SPORT Handling AWD
38,644 mi
Dublin, OH
Fair Deal
$44,929
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 49,435
- Stock #:
- R182129A
- VIN:
- 2T2YZMDA8NC335941
2022 Lexus RX
350 F SPORT Handling AWD
49,435 mi
Miami, FL
Great Deal
$37,988
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 73,665
- Stock #:
- NC348872
- VIN:
- 2T2YZMDA3NC348872
Price drop
-$2,685
2022 Lexus RX
350 F SPORT Handling AWD
73,665 mi
Parker, CO
Fair Deal
$40,599
$38,613
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 45,426
- Stock #:
- C353410
- VIN:
- 2T2YZMDA1NC353410
2022 Lexus RX
350 F SPORT Handling AWD
45,426 mi
Orlando, FL
Good Deal
$41,190
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red w/Scored Aluminum Trim
- Transmission:
- Automatic
- Mileage:
- 65,217
- Stock #:
- 10085
- VIN:
- 2T2YZMDA5NC330695
2022 Lexus RX
350 F SPORT Handling AWD
65,217 mi
Bountiful, UT
Great Deal
$36,244
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 23,197
- Stock #:
- 341873
- VIN:
- 2T2YZMDA3NC341873
2022 Lexus RX
350 F SPORT Handling AWD
23,197 mi
Madison, NC
Fair Deal
$45,865
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Tan)
- Transmission:
- Automatic
- Mileage:
- 14,375
- Stock #:
- CNC320553
- VIN:
- 2T2YZMDA1NC320553
2022 Lexus RX
350 F SPORT Handling AWD
14,375 mi
Nederland, TX
Good Deal
$46,916
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 68,454
- Stock #:
- T57679A
- VIN:
- 2T2YZMDA5NC320815
New arrival
2022 Lexus RX
350 F SPORT Handling AWD
68,454 mi
Eugene, OR
Fair Deal
$39,248
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 58,648
- Stock #:
- P3187
- VIN:
- 2T2YZMDA1NC313697
New arrival
2022 Lexus RX
350 F SPORT Handling AWD
58,648 mi
Tuscaloosa, AL
Fair Deal
$42,257
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 83,000
- Stock #:
- 4845
- VIN:
- 2T2YZMDA5NC319907
2022 Lexus RX
350 F SPORT Handling AWD
83,000 mi
Kissimmee, FL
Good Deal
$33,050
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 52,204
- Stock #:
- NC342162
- VIN:
- 2T2YZMDA8NC342162
New arrival
2022 Lexus RX
350 F SPORT Handling AWD
52,204 mi
Arlington, TX
Fair Deal
$41,374
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 45,934
- Stock #:
- NLRTNC349971
- VIN:
- 2T2YZMDAXNC349971
Price drop
-$895
2022 Lexus RX
350 F SPORT Handling AWD
45,934 mi
Roswell, GA
Good Deal
$44,564
$43,669
FAQs
How much does the Lexus RX 350 F SPORT Handling AWD cost?
The average Lexus RX 350 F SPORT Handling AWD costs about $38,608.03. The average price has decreased by -4.5% since last year. The 418 for sale on CarGurus range from $27,410 to $64,983 in price.
How many Lexus RX 350 F SPORT Handling AWD vehicles have no reported accidents or damage?
349 out of 418 for sale have no reported accidents or damage.
What is the fuel economy of the Lexus RX 350 F SPORT Handling AWD?
Depending on the engine and options, the Lexus RX 350 F SPORT Handling AWD gets between 22 and 24 MPG/MPGe.
What fuel types are available?
Gasoline engines are available.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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