worst things- how it looks, how it handles, and how others will despise you for owning it. The best- you can crash it, burn it, or give it to a homeless guy to live in, then you won't be burdened with that eyesore of a vehicle. You should upgrade to a used Pontiac Aztec, or a Buick Rendezvouz.
The Previa is one of the most over-engineered and over- built vehicles that Toyota ever produced. That's a good thing, as it will last forever. That said, have the SAD (supplemental auxiliary shaft) shaft inspected. It's driven from the center mounted engine and powers the A/C compressor, power steering, Alternator, and fan - all of which are up front. Being a former Toyota service manager, I saw countless Previas come in with over 500,000 miles showing on their odometers, yet they were running perfectly.
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