Infiniti's full-size QX56 SUV received an updated exterior design for 2008, as well as some interior upgrades. A 320-horsepower, 5.6-liter V8 engine provided plenty of power for the two-wheel-drive Base model. Infiniti noted that the engine was one of the strongest it has ever built, with a reinforced aluminum block and a forged-steel crankshaft.

New interior features for 2008 included redesigned gauges for the instrument cluster and a larger eight-inch screen for the optional DVD entertainment system. There was also a greater use of wood trim to add to the interior's luxury feel.

Other standard interior features included leather-appointed seating, a heated steering wheel, heated front seats with power adjustment (10-way for the driver, eight-way for the passenger), and a 12-speaker Bose premium audio system with a 9.3-gigabyte built-in hard drive that can store nearly 3,000 songs. The QX56 also came with three years of complimentary XM satellite radio service and XM NavTraffic service.

Exterior upgrades for 2008 included a new grille, new front and rear fascias, updated fog lights, a new roof rack, and new 20-inch chrome wheels.