The SE-R is one of two sport-focused versions of the Sentra, along with the top-tier SE-R Spec V. The SE-R is similarly equipped to the lower-level LS, with standard features like leather upholstery, a leather-trimmed steering wheel, cruise control, and an alarm system. The SE-R is differentiated from the LS by a number of performance and appearance upgrades, like 17-inch wheels, a firmer suspension, larger brakes, a lower body kit, special sport seats, aluminum-trimmed pedals, and oil pressure and G-force gauges.

Options at this level include a sunroof, a spoiler, an upgraded 340-watt Rockford Fosgate sound system, Bluetooth, and satellite radio.

The SE-R is powered by a 2.5-liter four-cylinder engine, which generates 177 horsepower and 172 pound-feet of torque. This engine is mated to a continuously variable transmission.