The Toyota Sienna lineup receives several revisions for 2006.  Both the front and rear fascias have been restyled, and more safety features have been added.

The long Sienna lineup begins with the CE.  AWD is not offered on this trim, but seven and eight passenger seating configurations are available.  The CE is equipped with dual sliding doors, front and rear air conditioning, a six speaker audio system, keyless entry, and full power accessories.  Toyota has added its Star Safety System to all models, complete with ABS with Electronic Brake-force Distribution and Brake Assist.  The Advanced Airbag System, with front seat-side and side-curtain airbags, is now standard across the board.

The Sienna houses a 3.3 liter DOHC V-6, which provides 215 horsepower and 222 pound-feet of torque.  All Siennas use a five speed electronically controlled automatic transmission, and the non-AWD models are front wheel drive.