I would say yes. I think with the proper care you possibly reach 200,000. I think you can always expect belts and smaller parts to need to be replaced but I think yes.

Without doubt.  I've owned 3 cars lasting over 300,000 miles.  Most important is regular oil changes (3000 miles), correct air pressure, park in a garage, and most important...no collisions.

Yea it's possible as long as  ur vehicle is properly maintained. And wearing parts  are taken care of before they start affecting others.

They have a poor history of rear differential failures!

Absolutely.  I owned a '94 that is now closing in on 200k, & currently own a '97 with 165k+ on the clock.  The rear differential issues are likely due to rear seals that have fallen into neglect.  They should be replaced at about 100k mark unless they show signs of leakage prior to that.  It's entirely possible late-model Explorers could have weaker rear differentials than prior models, and if used a lot for towing or to accelerate hard could become stressed to a point of failure.